STAT3 inhibition ameliorates renal interstitial inflammation in MRL/lpr mice with diffuse proliferative lupus nephritis

STAT3 inhibition ameliorates renal interstitial inflammation in MRL/lpr mice with diffuse proliferative lupus nephritis

Background and objectives Acute kidney injury (AKI) is one of the most common and severe clinical syndromes of diffuse proliferative lupus nephritis (DPLN), of which poor prognosis is indicated by aggravated renal function deterioration. However, the specific therapy and mechanisms of AKI in DPLN re...

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Bibliographic Details
Main Authors: Jianfen Zhu, Yijing Chen, Yulan Chen, Yinqiu Lv, Tianxin Chen
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Renal Failure
Subjects:
STAT3
AKI
lupus nephritis
renal interstitial
Online Access:https://www.tandfonline.com/doi/10.1080/0886022X.2024.2358187
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