Inhibiting the Interaction Between Phospholipase A2 and Phospholipid Serine as a Potential Therapeutic Method for Pneumonia

Inhibiting the Interaction Between Phospholipase A2 and Phospholipid Serine as a Potential Therapeutic Method for Pneumonia

Pneumonia is a severe lower respiratory tract infection. This study demonstrates that phospholipase A2 (PLA2), a potential biomarker for pneumonia, contributes to alveoli damage by hydrolyzing pulmonary surfactant phospholipids. This process impairs gas exchange and generates hemolytic phospholipids...

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Bibliographic Details
Main Authors:	Jianyu Wang, Huanchun Xing, Lin Wang, Zhongxing Xu, Xin Sui, Yuan Luo, Jun Yang, Yongan Wang
Format:	Article
Language:	English
Published:	MDPI AG 2025-07-01
Series:	Current Issues in Molecular Biology
Subjects:	pneumonia alveolar surfactant lipopolysaccharides phospholipase A2 inhibitor alveolar macrophages antibiotic resistance
Online Access:	https://www.mdpi.com/1467-3045/47/7/516
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