24-hour rhythms of DNA methylation and their relation with rhythms of RNA expression in the human dorsolateral prefrontal cortex.

24-hour rhythms of DNA methylation and their relation with rhythms of RNA expression in the human dorsolateral prefrontal cortex.

Circadian rhythms modulate the biology of many human tissues, including brain tissues, and are driven by a near 24-hour transcriptional feedback loop. These rhythms are paralleled by 24-hour rhythms of large portions of the transcriptome. The role of dynamic DNA methylation in influencing these rhyt...

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Bibliographic Details
Main Authors: Andrew S P Lim, Gyan P Srivastava, Lei Yu, Lori B Chibnik, Jishu Xu, Aron S Buchman, Julie A Schneider, Amanda J Myers, David A Bennett, Philip L De Jager
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-11-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1004792&type=printable
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