The association of PTEN/PI3K/Akt pathway gene expression with insulin indices in adipose tissues of non-diabetic female adults: a cross-sectional study

The association of PTEN/PI3K/Akt pathway gene expression with insulin indices in adipose tissues of non-diabetic female adults: a cross-sectional study

Abstract Insulin resistance (IR) is a complex metabolic condition that serves as a common thread connecting type 2 diabetes (T2DM), metabolic syndrome (MetS), cardiovascular disease (CVD), and even certain cancer outcomes. Understanding and addressing IR is crucial for the prevention and management...

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Main Authors: Maryam Zarkesh, Romina Saba, Hamidreza Aghazadeh, Farshad Teymoori, Mahdi Akbarzadeh, Golaleh Asghari, Marzieh Montazeri, Asghar Ghasemi, Emad Yuzbashian, Azita Zadeh-Vakili, Mehdi Hedayati, Alireza Khalaj
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Phosphatase and tensin homologue
Phosphatidylinositol-3-kinase
AKT serine/Threonine kinase
Insulin resistance
Adipose tissues
Females
Online Access:https://doi.org/10.1038/s41598-025-05233-4
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