Total Pancreatectomy for Ampullary Adenocarcinoma in a 74-Year-Old Patient: Case Report and Literature Review

Primary ampullary neoplasms have origin in the ampulla of Vater, an anatomical structure where the common bile duct and the pancreatic duct join together as a common channel. It represents <0.5% of all gastrointestinal cancers and approximately 7% of all periampullary cancers. The adenocarcinomas...

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Main Authors: Gabriela A. Arroyo Murillo, Eleonore Choppin De Janvry, Manuela Garofalo, Fatima Della Pietra
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Surgery
Online Access:http://dx.doi.org/10.1155/2020/8879609
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author Gabriela A. Arroyo Murillo
Eleonore Choppin De Janvry
Manuela Garofalo
Fatima Della Pietra
author_facet Gabriela A. Arroyo Murillo
Eleonore Choppin De Janvry
Manuela Garofalo
Fatima Della Pietra
author_sort Gabriela A. Arroyo Murillo
collection DOAJ
description Primary ampullary neoplasms have origin in the ampulla of Vater, an anatomical structure where the common bile duct and the pancreatic duct join together as a common channel. It represents <0.5% of all gastrointestinal cancers and approximately 7% of all periampullary cancers. The adenocarcinomas arising in this region originate from different epithelial cellular constituents present at the site, the histopathological classification encompass: intestinal type, pancreaticobiliary type, and mixed type. Pancreaticoduodenectomy is the treatment of choice when there is an overt or highly suspicious malignant behaviour. We present here the case of a 74-year-old male patient who presented to our department for further investigation of obstructive jaundice and a pancreatic mass associated with a six-month history of significant weight loss and mild epigastric pain. Eventually, a total splenopancreatectomy was performed given the extension of structural anomalies of the organ secondary to an ampullary adenocarcinoma.
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publishDate 2020-01-01
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series Case Reports in Surgery
spelling doaj-art-e695b804ca754e8d91a33cee118781b62025-02-03T06:43:44ZengWileyCase Reports in Surgery2090-69002090-69192020-01-01202010.1155/2020/88796098879609Total Pancreatectomy for Ampullary Adenocarcinoma in a 74-Year-Old Patient: Case Report and Literature ReviewGabriela A. Arroyo Murillo0Eleonore Choppin De Janvry1Manuela Garofalo2Fatima Della Pietra3General Surgery and Organ Transplantation Unit, Department of Surgery, University of Rome La Sapienza, Rome, ItalyGeneral Surgery and Organ Transplantation Unit, Department of Surgery, University of Rome La Sapienza, Rome, ItalyGeneral Surgery and Organ Transplantation Unit, Department of Surgery, University of Rome La Sapienza, Rome, ItalyGeneral Surgery and Organ Transplantation Unit, Department of Surgery, University of Rome La Sapienza, Rome, ItalyPrimary ampullary neoplasms have origin in the ampulla of Vater, an anatomical structure where the common bile duct and the pancreatic duct join together as a common channel. It represents <0.5% of all gastrointestinal cancers and approximately 7% of all periampullary cancers. The adenocarcinomas arising in this region originate from different epithelial cellular constituents present at the site, the histopathological classification encompass: intestinal type, pancreaticobiliary type, and mixed type. Pancreaticoduodenectomy is the treatment of choice when there is an overt or highly suspicious malignant behaviour. We present here the case of a 74-year-old male patient who presented to our department for further investigation of obstructive jaundice and a pancreatic mass associated with a six-month history of significant weight loss and mild epigastric pain. Eventually, a total splenopancreatectomy was performed given the extension of structural anomalies of the organ secondary to an ampullary adenocarcinoma.http://dx.doi.org/10.1155/2020/8879609
spellingShingle Gabriela A. Arroyo Murillo
Eleonore Choppin De Janvry
Manuela Garofalo
Fatima Della Pietra
Total Pancreatectomy for Ampullary Adenocarcinoma in a 74-Year-Old Patient: Case Report and Literature Review
Case Reports in Surgery
title Total Pancreatectomy for Ampullary Adenocarcinoma in a 74-Year-Old Patient: Case Report and Literature Review
title_full Total Pancreatectomy for Ampullary Adenocarcinoma in a 74-Year-Old Patient: Case Report and Literature Review
title_fullStr Total Pancreatectomy for Ampullary Adenocarcinoma in a 74-Year-Old Patient: Case Report and Literature Review
title_full_unstemmed Total Pancreatectomy for Ampullary Adenocarcinoma in a 74-Year-Old Patient: Case Report and Literature Review
title_short Total Pancreatectomy for Ampullary Adenocarcinoma in a 74-Year-Old Patient: Case Report and Literature Review
title_sort total pancreatectomy for ampullary adenocarcinoma in a 74 year old patient case report and literature review
url http://dx.doi.org/10.1155/2020/8879609
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