Risk Factors in Intraepithelial Lesions of the Cervix

<strong>Foundation:</strong> the risk factors of intraepithelial lesions behave similar to those of cervical cancer. <strong><br />Objective:</strong> to identify the influence of different risk factors related to the appearance of intraepithelial lesions of the cervix....

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Main Authors: Martha Palma Osorio, Alejandro David Romero Flores, Ana Isabel Torres Mesa
Format: Article
Language:Spanish
Published: Universidad de las Ciencias Médicas de Cienfuegos 2019-12-01
Series:Revista Finlay
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Online Access:https://revfinlay.sld.cu/index.php/finlay/article/view/693
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author Martha Palma Osorio
Alejandro David Romero Flores
Ana Isabel Torres Mesa
author_facet Martha Palma Osorio
Alejandro David Romero Flores
Ana Isabel Torres Mesa
author_sort Martha Palma Osorio
collection DOAJ
description <strong>Foundation:</strong> the risk factors of intraepithelial lesions behave similar to those of cervical cancer. <strong><br />Objective:</strong> to identify the influence of different risk factors related to the appearance of intraepithelial lesions of the cervix. <br /><strong>Method:</strong> an observational case-control study was carried out in the Gustavo Aldereguía Teaching Polyclinic of the Granma province in the period from January 1, 2016 to June 30, 2017. The 105 patients with cervical intraepithelial neoplasia were defined as cases histopathologically confirmed and as controls to women who underwent the cytological test, selected by simple random sampling. Each patient was performed: interview, physical examination and diagnostic means. For the analysis of risk factors, a univariate and multivariate strategy was used. Explanatory variables were defined as factors considered as hypothetically risky which would be subject to evaluation. The appearance of intraepithelial neoplasia was considered as a response variable. Punctual and 95 % confidence interval estimates were obtained. <br /><strong>Results:</strong> vaginal sepsis and early menarche were noticeable, however not the use of condoms, human papillomavirus infection, oral contraception, age, intrauterine device and smoking as indifferent factors. Erosion and vaginal sepsis were the most significant due to the logistic regression model. There were interactions between cervicitis, multiple sexual partners and smoking; moderately significant were age and early menarche; cervicitis and erosion, human papillomavirus infection and multiple sexual partners. <strong><br />Conclusions</strong>: it was determined that vaginal sepsis and cervical erosion presented a statistically significant and important association with the probability of the appearance of intraepithelial lesions of the cervix.
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spelling doaj-art-e691cd65ad0d43f69505a53d82650d932025-01-30T21:22:00ZspaUniversidad de las Ciencias Médicas de CienfuegosRevista Finlay2221-24342019-12-0194291305428Risk Factors in Intraepithelial Lesions of the CervixMartha Palma Osorio0Alejandro David Romero Flores1Ana Isabel Torres Mesa2Policlínico Docente Gustavo Aldereguía Lima. Granma.Policlínico Docente Gustavo Aldereguía Lima. Granma.Policlínico Docente Gustavo Aldereguía Lima. Granma.<strong>Foundation:</strong> the risk factors of intraepithelial lesions behave similar to those of cervical cancer. <strong><br />Objective:</strong> to identify the influence of different risk factors related to the appearance of intraepithelial lesions of the cervix. <br /><strong>Method:</strong> an observational case-control study was carried out in the Gustavo Aldereguía Teaching Polyclinic of the Granma province in the period from January 1, 2016 to June 30, 2017. The 105 patients with cervical intraepithelial neoplasia were defined as cases histopathologically confirmed and as controls to women who underwent the cytological test, selected by simple random sampling. Each patient was performed: interview, physical examination and diagnostic means. For the analysis of risk factors, a univariate and multivariate strategy was used. Explanatory variables were defined as factors considered as hypothetically risky which would be subject to evaluation. The appearance of intraepithelial neoplasia was considered as a response variable. Punctual and 95 % confidence interval estimates were obtained. <br /><strong>Results:</strong> vaginal sepsis and early menarche were noticeable, however not the use of condoms, human papillomavirus infection, oral contraception, age, intrauterine device and smoking as indifferent factors. Erosion and vaginal sepsis were the most significant due to the logistic regression model. There were interactions between cervicitis, multiple sexual partners and smoking; moderately significant were age and early menarche; cervicitis and erosion, human papillomavirus infection and multiple sexual partners. <strong><br />Conclusions</strong>: it was determined that vaginal sepsis and cervical erosion presented a statistically significant and important association with the probability of the appearance of intraepithelial lesions of the cervix.https://revfinlay.sld.cu/index.php/finlay/article/view/693factores de riesgolesiones intraepiteliales escamosas de cuello uterino
spellingShingle Martha Palma Osorio
Alejandro David Romero Flores
Ana Isabel Torres Mesa
Risk Factors in Intraepithelial Lesions of the Cervix
Revista Finlay
factores de riesgo
lesiones intraepiteliales escamosas de cuello uterino
title Risk Factors in Intraepithelial Lesions of the Cervix
title_full Risk Factors in Intraepithelial Lesions of the Cervix
title_fullStr Risk Factors in Intraepithelial Lesions of the Cervix
title_full_unstemmed Risk Factors in Intraepithelial Lesions of the Cervix
title_short Risk Factors in Intraepithelial Lesions of the Cervix
title_sort risk factors in intraepithelial lesions of the cervix
topic factores de riesgo
lesiones intraepiteliales escamosas de cuello uterino
url https://revfinlay.sld.cu/index.php/finlay/article/view/693
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AT alejandrodavidromeroflores riskfactorsinintraepitheliallesionsofthecervix
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