Genetic diversity of Toscana virus glycoproteins affects the kinetics of virus entry and the infectivity of newly produced virions

Abstract Toscana virus (TOSV) is a pathogenic and transmissible Phlebovirus of the Bunyavirales order. To date, two principal genetic lineages (A and B) have been identified and the impact of TOSV genetic diversity on its biology is still unknown. We used a reverse genetic approach based on two TOSV...

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Bibliographic Details
Main Authors: Adrien Thiesson, Marie-Pierre Confort, Sophie Desloire, Alain Kohl, Frédérick Arnaud, Maxime Ratinier
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:npj Viruses
Online Access:https://doi.org/10.1038/s44298-025-00113-0
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