A Quarter Century of Liver Transplantation: Learning from Livers
Liver transplantation has emerged as a powerful tool to increase the understanding of physiological and pathophysiological processes in the liver. Transplantation for metabolic diseases with resolution of the disease process has been the ultimate proof of the hepatic source of the defect. Recurrence...
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| Main Author: | |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
1989-01-01
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| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/1989/695761 |
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| Summary: | Liver transplantation has emerged as a powerful tool to increase
the understanding of physiological and pathophysiological processes in the liver.
Transplantation for metabolic diseases with resolution of the disease process has
been the ultimate proof of the hepatic source of the defect. Recurrence of the
primary disease in the liver following transplantation has furthered understanding
of the pathogenesis of hepatitis and the cell biology of hepatobiliary
tumours. The role of genetics and immune factors in the pathogenesis of alcoholic
I iver disease may be clarified with the increasing numbers of patients transplanted
for alcoholic cirrhosis. Normal gallbladder motility in the denervated
transplanted liver questions the role of neuronal influences on gallbladder
function. Finally, experimental liver transplantation in animals has been used as
a tool to study metabolic problems. |
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| ISSN: | 0835-7900 |