Researching the effects of methylprednisoione (mp) and dimethyl sulphoxide (dmso) on the prevention of peritoneal adhesions in rabbits
The purpose of the study was to evaluate the effect of methylprednisoione (MP) and dimethyl sulphoxide (DMSO) on the prevention of peritoneal adhesions in rabbits. Thirtysix rabbits were used. The rabbits divided into three groups, each having 12 rabbits. In all rabbits in three groups, midline lapa...
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Selcuk University Press
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| Series: | Eurasian Journal of Veterinary Sciences |
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| author | Fahrettin Alkan Yılmaz Koç İlhami Çelik Muharrem Erol M.Faruk Aydın |
| author_facet | Fahrettin Alkan Yılmaz Koç İlhami Çelik Muharrem Erol M.Faruk Aydın |
| author_sort | Fahrettin Alkan |
| collection | DOAJ |
| description | The purpose of the study was to evaluate the effect of methylprednisoione (MP) and dimethyl sulphoxide (DMSO) on the prevention of peritoneal adhesions in rabbits. Thirtysix rabbits were used. The rabbits divided into three groups, each having 12 rabbits. In all rabbits in three groups, midline laparotomies were applied. Six- eight longitudinal incision were made on the left peritoneal surface. Area that 1x2cm, was excised from, the right peritoneal surface. Group 1, 2, and, 3 were intraperitoneal^ administered 5 ml/kg of the physiologycal saline (0.9%NaCI solution), 15 mg/kg methylprednisoione in 5 ml of the physiologycal saline, and 1 g/kg dimethyl sulphoxide in 5 ml of the physiologycal saline respectively following the laparotomy, and injections were continued for 5 days after laparotomy. Fourteen days after surgery, all rabbits underwent via a paramedian incision in order to evaluate whether the presence and extend of the adhesions. In the defective areas were taked the biopsy samples from the hystologic researchs. The results suggest that the MP and DMSO used in this study significantly decrease the incidence and degree of peritoneal adhesions when compared to the saline group. |
| format | Article |
| id | doaj-art-e659a9a865ca4eaf9c717d97f887caf2 |
| institution | Kabale University |
| issn | 1309-6958 2146-1953 |
| language | English |
| publisher | Selcuk University Press |
| record_format | Article |
| series | Eurasian Journal of Veterinary Sciences |
| spelling | doaj-art-e659a9a865ca4eaf9c717d97f887caf22025-02-03T11:25:42ZengSelcuk University PressEurasian Journal of Veterinary Sciences1309-69582146-1953232737943Researching the effects of methylprednisoione (mp) and dimethyl sulphoxide (dmso) on the prevention of peritoneal adhesions in rabbitsFahrettin Alkan0Yılmaz Koç1İlhami Çelik2Muharrem Erol3M.Faruk Aydın4Selçuk Üniversitesi Veteriner Fakültesi, Cerrahi Anabilim Dalı, KONYASelçuk Üniversitesi Veteriner Fakültesi, Cerrahi Anabilim Dalı, KONYASelçuk Üniversitesi Veteriner Fakültesi, Histoloji ve Embriyoloji Anabilim Dalı, KONYASelçuk Üniversitesi Veteriner Fakültesi, Cerrahi Anabilim Dalı, KONYAHarran Üniversitesi, Veteriner Fakültesi Histoloji ve Embriyoloji Anabilim Dalı, URFAThe purpose of the study was to evaluate the effect of methylprednisoione (MP) and dimethyl sulphoxide (DMSO) on the prevention of peritoneal adhesions in rabbits. Thirtysix rabbits were used. The rabbits divided into three groups, each having 12 rabbits. In all rabbits in three groups, midline laparotomies were applied. Six- eight longitudinal incision were made on the left peritoneal surface. Area that 1x2cm, was excised from, the right peritoneal surface. Group 1, 2, and, 3 were intraperitoneal^ administered 5 ml/kg of the physiologycal saline (0.9%NaCI solution), 15 mg/kg methylprednisoione in 5 ml of the physiologycal saline, and 1 g/kg dimethyl sulphoxide in 5 ml of the physiologycal saline respectively following the laparotomy, and injections were continued for 5 days after laparotomy. Fourteen days after surgery, all rabbits underwent via a paramedian incision in order to evaluate whether the presence and extend of the adhesions. In the defective areas were taked the biopsy samples from the hystologic researchs. The results suggest that the MP and DMSO used in this study significantly decrease the incidence and degree of peritoneal adhesions when compared to the saline group.http://eurasianjvetsci.org/pdf.php3?id=43rabbitadhesionmetnylprednisoionedimethyl sulphoxide |
| spellingShingle | Fahrettin Alkan Yılmaz Koç İlhami Çelik Muharrem Erol M.Faruk Aydın Researching the effects of methylprednisoione (mp) and dimethyl sulphoxide (dmso) on the prevention of peritoneal adhesions in rabbits Eurasian Journal of Veterinary Sciences rabbit adhesion metnylprednisoione dimethyl sulphoxide |
| title | Researching the effects of methylprednisoione (mp) and dimethyl sulphoxide (dmso) on the prevention of peritoneal adhesions in rabbits |
| title_full | Researching the effects of methylprednisoione (mp) and dimethyl sulphoxide (dmso) on the prevention of peritoneal adhesions in rabbits |
| title_fullStr | Researching the effects of methylprednisoione (mp) and dimethyl sulphoxide (dmso) on the prevention of peritoneal adhesions in rabbits |
| title_full_unstemmed | Researching the effects of methylprednisoione (mp) and dimethyl sulphoxide (dmso) on the prevention of peritoneal adhesions in rabbits |
| title_short | Researching the effects of methylprednisoione (mp) and dimethyl sulphoxide (dmso) on the prevention of peritoneal adhesions in rabbits |
| title_sort | researching the effects of methylprednisoione mp and dimethyl sulphoxide dmso on the prevention of peritoneal adhesions in rabbits |
| topic | rabbit adhesion metnylprednisoione dimethyl sulphoxide |
| url | http://eurasianjvetsci.org/pdf.php3?id=43 |
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