Involvement of Urokinase-Type Plasminogen Activator Receptor in the Formation of a Profibrotic Microenvironment in the Epicardial Region
The study of the mechanisms of development and progression of fibrosis is one of the key directions of modern cardiology. Our work suggests that the urokinase receptor (uPAR) is involved in the regulation of mesothelial cell activity and epicardial fibrosis development, which, when interacting with...
Saved in:
| Main Authors: | K. V. Dergilev, Z. I. Tsokolayeva, I. B. Beloglazova, Yu. D. Vasilets, D. O. Traktuyev, B. N. Kulbitsky, E. V. Parfenova |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
2021-12-01
|
| Series: | Общая реаниматология |
| Subjects: | |
| Online Access: | https://www.reanimatology.com/rmt/article/view/2159 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Role of Urokinase-Type Plasminogen Activator Receptor in the Regulation of Angiogenic Properties of Sca1+ Vasculogenic Progenitor Cells
by: К. V. Dergilev, et al.
Published: (2022-04-01) -
Intramyocardial Injection of Plasmid Encoding Platelet Growth Factor Increases Epicardial-Mediated Post Infarction Myocardial Vascularization (Experimental Study)
by: K. V. Dergilev, et al.
Published: (2020-12-01) -
Association of soluble urokinase plasminogen activator receptor and epidermal growth factor with histopathological findings of kidney biopsy: a single-center study
by: Eman Nagy, et al.
Published: (2025-07-01) -
Effect of Plasma Soluble Urokinase-Type Plasminogen Activator Receptor and Plasminogen Activator Inhibitor-1 Levels in the Plasma of Babylon Women with Breast Cancer
by: Sheerin H. Abbas, et al.
Published: (2025-01-01) -
Safety and efficacy of tirofiban after intravenous thrombolysis with urokinase in patients with acute ischemic stroke
by: Dian Qu, et al.
Published: (2025-03-01)