High glycemic variability is associated with a reduced T cell cytokine response to influenza A virus

Summary: Diabetes mellitus significantly increases the risk of severe respiratory virus disease like influenza and COVID-19. Early evidence suggests that this susceptibility to respiratory viral disease is driven by glycemic variability, rather than average blood glucose levels. Here, we use blood s...

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Main Authors: Marcus Z.W. Tong, Katina D. Hulme, Soi Cheng Law, Ellesandra Noye, Emily S. Dorey, Keng Yih Chew, Louise C. Rowntree, Carolien E. van de Sandt, Katherine Kedzierska, Marco Goeijenbier, Katharina Ronacher, Fawaz Alzaid, Jean-Baptiste Julla, Jean-Pierre Riveline, Katie E. Lineburg, Corey Smith, Emma J. Grant, Stephanie Gras, Linda A. Gallo, Helen L. Barrett, Kirsty R. Short
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:iScience
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224023915
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