The performance of sCD25 and CTLs degranulation test for screening patients with primary hemophagocytic lymphohistiocytosis: a large-scale multicenter study in China

The performance of sCD25 and CTLs degranulation test for screening patients with primary hemophagocytic lymphohistiocytosis: a large-scale multicenter study in China

BackgroundHemophagocytic lymphohistiocytosis can be classified as primary HLH (pHLH) and secondary HLH. The early identify of pHLH can facilitate successful treatment. The rapid screening test greatly facilitated the diagnostic process of pHLH. However, there are rare studies to explore the ability...

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Bibliographic Details
Main Authors: Wenshuai Zheng, Zhaoguang Chen, Yibo Cai, Zongze Wu, Zhenlan Du, Xiaohong Li, Beicheng Li, Shibin Zhu, Hongmei Ning
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
hemophagocytic lymphohistiocytosis
sCD25
cytotoxic T lymphocytes degranulation test
screening test
China
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1616541/full
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