Effectiveness of isometric muscle training combined with manual lymphatic drainage on secondary lower extremity lymphedema following gynecologic cancer surgery

ObjectiveTo investigate the effects of isokinetic strength training combined with manual lymphatic drainage (MLD) on leg circumference, walking ability and muscle strength in patients with secondary lymphedema following gynecologic cancer surgery.DesignRandomized controlled trial.SettingInpatient re...

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Main Authors: Jiahui Ma, Hewei Wang, Yilan Li, Xiang Guo, Mengjia Xie, Xinxin Wang, Luxi Mao, Dapeng Xing, Li Shen, Dan Chen, Jingxin Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Bioengineering and Biotechnology
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Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2025.1568003/full
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author Jiahui Ma
Hewei Wang
Yilan Li
Xiang Guo
Mengjia Xie
Xinxin Wang
Luxi Mao
Dapeng Xing
Li Shen
Dan Chen
Jingxin Wang
author_facet Jiahui Ma
Hewei Wang
Yilan Li
Xiang Guo
Mengjia Xie
Xinxin Wang
Luxi Mao
Dapeng Xing
Li Shen
Dan Chen
Jingxin Wang
author_sort Jiahui Ma
collection DOAJ
description ObjectiveTo investigate the effects of isokinetic strength training combined with manual lymphatic drainage (MLD) on leg circumference, walking ability and muscle strength in patients with secondary lymphedema following gynecologic cancer surgery.DesignRandomized controlled trial.SettingInpatient rehabilitation department.ParticipantsSixty-six patients with secondary lymphedema of the lower extremities following gynecologic cancer surgery were randomly allocated into an experimental group and a control group, each comprising 33 patients.InterventionsThe control group participated in a 4-week standardized MLD program. In addition to the MLD program, participants in the experimental group received additional isokinetic strength training for 20 min daily over the same 4-week period.OutcomesLower limb volume derived from the circumference measurements, Holden Gait Scale and Lovett muscle strength grading.ResultsPrior to the intervention, no statistically significant differences were observed between the two groups across all outcomes (P > 0.05). Post-intervention, statistically significant improvements were noted in the experimental group compared to the control group with respect to reduced lower extremity volume, improved walking ability, and increased muscle strength (P < 0.05).ConclusionFor patients with secondary lower limb lymphedema following gynecological tumor surgery, a combination of isokinetic strength training and MLD has been found to be more effective than MLD alone in reducing edema, improving walking ability, and enhancing muscle strength.
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spelling doaj-art-e64c45a2fa734d059d357c49eaab2c022025-08-20T03:49:40ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852025-05-011310.3389/fbioe.2025.15680031568003Effectiveness of isometric muscle training combined with manual lymphatic drainage on secondary lower extremity lymphedema following gynecologic cancer surgeryJiahui Ma0Hewei Wang1Yilan Li2Xiang Guo3Mengjia Xie4Xinxin Wang5Luxi Mao6Dapeng Xing7Li Shen8Dan Chen9Jingxin Wang10Department of Rehabilitation Medicine, Zhengzhou Central Hospital Affiliated Zhengzhou University, Zhengzhou, ChinaDepartment of Rehabilitation, Huashan Hospital, Fudan University, Shanghai, ChinaDepartment of Rehabilitation, Hangzhou Linping Hospital of Traditional Chinese and Western Medicine, Hangzhou, ChinaDepartment of Rehabilitation, Hangzhou Linping Hospital of Traditional Chinese and Western Medicine, Hangzhou, ChinaDepartment of Rehabilitation, Hangzhou Linping Hospital of Traditional Chinese and Western Medicine, Hangzhou, ChinaDepartment of Rehabilitation, Hangzhou Linping Hospital of Traditional Chinese and Western Medicine, Hangzhou, ChinaDepartment of Rehabilitation, Hangzhou Linping Hospital of Traditional Chinese and Western Medicine, Hangzhou, ChinaDepartment of Rehabilitation, Hangzhou Linping Hospital of Traditional Chinese and Western Medicine, Hangzhou, ChinaDepartment of Rehabilitation, Huashan Hospital, Fudan University, Shanghai, ChinaDepartment of Rehabilitation Medicine, Jing’an District Central Hospital of Shanghai, Shanghai, ChinaDepartment of Rehabilitation, Hangzhou Linping Hospital of Traditional Chinese and Western Medicine, Hangzhou, ChinaObjectiveTo investigate the effects of isokinetic strength training combined with manual lymphatic drainage (MLD) on leg circumference, walking ability and muscle strength in patients with secondary lymphedema following gynecologic cancer surgery.DesignRandomized controlled trial.SettingInpatient rehabilitation department.ParticipantsSixty-six patients with secondary lymphedema of the lower extremities following gynecologic cancer surgery were randomly allocated into an experimental group and a control group, each comprising 33 patients.InterventionsThe control group participated in a 4-week standardized MLD program. In addition to the MLD program, participants in the experimental group received additional isokinetic strength training for 20 min daily over the same 4-week period.OutcomesLower limb volume derived from the circumference measurements, Holden Gait Scale and Lovett muscle strength grading.ResultsPrior to the intervention, no statistically significant differences were observed between the two groups across all outcomes (P > 0.05). Post-intervention, statistically significant improvements were noted in the experimental group compared to the control group with respect to reduced lower extremity volume, improved walking ability, and increased muscle strength (P < 0.05).ConclusionFor patients with secondary lower limb lymphedema following gynecological tumor surgery, a combination of isokinetic strength training and MLD has been found to be more effective than MLD alone in reducing edema, improving walking ability, and enhancing muscle strength.https://www.frontiersin.org/articles/10.3389/fbioe.2025.1568003/fullsecondary lymphedemagynecologic cancerlower extremityisokinetic strength trainingmanual lymphatic drainage
spellingShingle Jiahui Ma
Hewei Wang
Yilan Li
Xiang Guo
Mengjia Xie
Xinxin Wang
Luxi Mao
Dapeng Xing
Li Shen
Dan Chen
Jingxin Wang
Effectiveness of isometric muscle training combined with manual lymphatic drainage on secondary lower extremity lymphedema following gynecologic cancer surgery
Frontiers in Bioengineering and Biotechnology
secondary lymphedema
gynecologic cancer
lower extremity
isokinetic strength training
manual lymphatic drainage
title Effectiveness of isometric muscle training combined with manual lymphatic drainage on secondary lower extremity lymphedema following gynecologic cancer surgery
title_full Effectiveness of isometric muscle training combined with manual lymphatic drainage on secondary lower extremity lymphedema following gynecologic cancer surgery
title_fullStr Effectiveness of isometric muscle training combined with manual lymphatic drainage on secondary lower extremity lymphedema following gynecologic cancer surgery
title_full_unstemmed Effectiveness of isometric muscle training combined with manual lymphatic drainage on secondary lower extremity lymphedema following gynecologic cancer surgery
title_short Effectiveness of isometric muscle training combined with manual lymphatic drainage on secondary lower extremity lymphedema following gynecologic cancer surgery
title_sort effectiveness of isometric muscle training combined with manual lymphatic drainage on secondary lower extremity lymphedema following gynecologic cancer surgery
topic secondary lymphedema
gynecologic cancer
lower extremity
isokinetic strength training
manual lymphatic drainage
url https://www.frontiersin.org/articles/10.3389/fbioe.2025.1568003/full
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