Preformation and epigenesis converge to specify primordial germ cell fate in the early Drosophila embryo.
A critical step in animal development is the specification of primordial germ cells (PGCs), the precursors of the germline. Two seemingly mutually exclusive mechanisms are implemented across the animal kingdom: epigenesis and preformation. In epigenesis, PGC specification is non-autonomous and depen...
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| Main Authors: | Megan M Colonnetta, Yogesh Goyal, Heath E Johnson, Sapna Syal, Paul Schedl, Girish Deshpande |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2022-01-01
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| Series: | PLoS Genetics |
| Online Access: | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1010002&type=printable |
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