Analyzing the relationship of RNA and DNA methylation with gene expression

Analyzing the relationship of RNA and DNA methylation with gene expression

Abstract Background DNA 5-methylcytosine (5mC) and RNA N6-methyladenosine (m6A) methylation are prevalent modifications in eukaryotes, both playing crucial roles in gene regulation. Recent studies have explored their crosstalk and impact on transcription. However, the intricate relationships among 5...

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Bibliographic Details
Main Authors: Shangqian Xie, Darren Hagen, Gabrielle M. Becker, Kimberly M. Davenport, Katie A. Shira, Morgan R. Stegemiller, Jacob W. Thorne, Sarem Khilji, Denise Konetchy, Patricia Villamediana, Brenda M. Murdoch, Stephanie D. McKay
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Genome Biology
Subjects:
5-methylcytosine
N6-methyladenosine
Methylation
RNA expression
Caruncle
Cow
Online Access:https://doi.org/10.1186/s13059-025-03617-3
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