Intrathecal interleukin-6 levels are associated with progressive disease and clinical severity in multiple sclerosis

Intrathecal interleukin-6 levels are associated with progressive disease and clinical severity in multiple sclerosis

Abstract Background MS is characterized by persistent central nervous system (CNS) inflammation. Investigating the CNS-compartmentalized inflammation associated with progressive MS could uncover new biomarkers and therapeutic targets. Cerebrospinal fluid (CSF) interleukin-6 (IL-6) can be markedly el...

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Bibliographic Details
Main Authors: Justine Itorralba, Koroboshka Brand-Arzamendi, Georges Saab, Alexandra Muccilli, Raphael Schneider
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Neurology
Subjects:
Multiple sclerosis
Interleukin-6
Cerebrospinal fluid
Disease progression
Neuroinflammation
Online Access:https://doi.org/10.1186/s12883-025-04145-0
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