DEFINITION OF CYTOSTATIC EFFECT OF PROTARGOLUM SOLUTIONS IN DIFFERENT CONCENTRATIONS ON HUMAN DERMAL FIBROBLASTS

This article presents the data on the effect of protargolum solutions in different concentrations on human dermal fibroblasts. For evaluation of the metabolic activity of the cells MTT-test was used. This test is based on the ability of NAD-H-adjective oxydoreductases to represent the amount of viab...

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Bibliographic Details
Main Authors: N. V. Mescheryakova, E. B. Dashinimaev, A. I. Marakhova
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2019-01-01
Series:Разработка и регистрация лекарственных средств
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Online Access:https://www.pharmjournal.ru/jour/article/view/172
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Summary:This article presents the data on the effect of protargolum solutions in different concentrations on human dermal fibroblasts. For evaluation of the metabolic activity of the cells MTT-test was used. This test is based on the ability of NAD-H-adjective oxydoreductases to represent the amount of viable cells. It was determined, that the critical concentration of protargolum solution, responsible for inhibitory effect on fibroblasts proliferation is on the range 2 · 10-2 - 5 · 10-1 mg/ml.
ISSN:2305-2066
2658-5049