Obstructive Sleep Apnea Patients Having Surgery Are Less Associated with Glaucoma
Objective. To investigate if different treatment strategy of obstructive sleep apnea (OSA) was associated glaucoma risk in Taiwanese population. Methods. Population-based retrospective cohort study was conducted using data sourced from the Longitudinal Health Insurance Database 2000. We included 252...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2014/838912 |
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| _version_ | 1832563054722678784 |
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| author | Hsin-Yi Chen Yue-Cune Chang Che-Chen Lin Fung-Chang Sung Wen-Chi Chen |
| author_facet | Hsin-Yi Chen Yue-Cune Chang Che-Chen Lin Fung-Chang Sung Wen-Chi Chen |
| author_sort | Hsin-Yi Chen |
| collection | DOAJ |
| description | Objective. To investigate if different treatment strategy of obstructive sleep apnea (OSA) was associated glaucoma risk in Taiwanese population. Methods. Population-based retrospective cohort study was conducted using data sourced from the Longitudinal Health Insurance Database 2000. We included 2528 OSA patients and randomly selected and matched 10112 subjects without OSA as the control cohort. The risk of glaucoma in OSA patients was investigated based on the managements of OSA (without treatment, with surgery, with continuous positive airway pressure (CPAP) treatment, and with multiple modalities). The multivariable Cox regression was used to estimate hazard ratio (HR) after adjusting for sex, age, hypertension, diabetes, hyperlipidemia, and coronary artery disease. Results. The adjusted HR of glaucoma for OSA patients was 1.88 (95% CI: 1.46–2.42), compared with controls. For patients without treatment, the adjusted HR was 2.15 (95% CI: 1.60–2.88). For patients with treatments, the adjusted HRs of glaucoma were not significantly different from controls, except for those with CPAP (adjusted HR = 1.65, 95% CI = 1.09–2.49). Conclusions. OSA is associated with an increased risk of glaucoma. However, surgery reduces slightly the glaucoma hazard for OSA patients. |
| format | Article |
| id | doaj-art-e5f96e6201ff4440a2a728173111b94f |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-e5f96e6201ff4440a2a728173111b94f2025-02-03T01:21:06ZengWileyJournal of Ophthalmology2090-004X2090-00582014-01-01201410.1155/2014/838912838912Obstructive Sleep Apnea Patients Having Surgery Are Less Associated with GlaucomaHsin-Yi Chen0Yue-Cune Chang1Che-Chen Lin2Fung-Chang Sung3Wen-Chi Chen4Graduate Institute of Clinical Medical Science, China Medical University, Taichung 404, TaiwanDepartment of Mathematics, Tamkang University, New Taipei City 25137, TaiwanManagement Office for Health Data, China Medical University Hospital, Taichung 404, TaiwanManagement Office for Health Data, China Medical University Hospital, Taichung 404, TaiwanGraduate Institute of Clinical Medical Science, China Medical University, Taichung 404, TaiwanObjective. To investigate if different treatment strategy of obstructive sleep apnea (OSA) was associated glaucoma risk in Taiwanese population. Methods. Population-based retrospective cohort study was conducted using data sourced from the Longitudinal Health Insurance Database 2000. We included 2528 OSA patients and randomly selected and matched 10112 subjects without OSA as the control cohort. The risk of glaucoma in OSA patients was investigated based on the managements of OSA (without treatment, with surgery, with continuous positive airway pressure (CPAP) treatment, and with multiple modalities). The multivariable Cox regression was used to estimate hazard ratio (HR) after adjusting for sex, age, hypertension, diabetes, hyperlipidemia, and coronary artery disease. Results. The adjusted HR of glaucoma for OSA patients was 1.88 (95% CI: 1.46–2.42), compared with controls. For patients without treatment, the adjusted HR was 2.15 (95% CI: 1.60–2.88). For patients with treatments, the adjusted HRs of glaucoma were not significantly different from controls, except for those with CPAP (adjusted HR = 1.65, 95% CI = 1.09–2.49). Conclusions. OSA is associated with an increased risk of glaucoma. However, surgery reduces slightly the glaucoma hazard for OSA patients.http://dx.doi.org/10.1155/2014/838912 |
| spellingShingle | Hsin-Yi Chen Yue-Cune Chang Che-Chen Lin Fung-Chang Sung Wen-Chi Chen Obstructive Sleep Apnea Patients Having Surgery Are Less Associated with Glaucoma Journal of Ophthalmology |
| title | Obstructive Sleep Apnea Patients Having Surgery Are Less Associated with Glaucoma |
| title_full | Obstructive Sleep Apnea Patients Having Surgery Are Less Associated with Glaucoma |
| title_fullStr | Obstructive Sleep Apnea Patients Having Surgery Are Less Associated with Glaucoma |
| title_full_unstemmed | Obstructive Sleep Apnea Patients Having Surgery Are Less Associated with Glaucoma |
| title_short | Obstructive Sleep Apnea Patients Having Surgery Are Less Associated with Glaucoma |
| title_sort | obstructive sleep apnea patients having surgery are less associated with glaucoma |
| url | http://dx.doi.org/10.1155/2014/838912 |
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