Long-Term Effect of Surgery in Graves’ Disease: 20 Years Experience in a Single Institution
The present study compared the long-term outcome of subtotal thyroidectomy (ST) to that of total thyroidectomy (TT) in Graves’ disease (GD). Patients with GD requiring surgery were divided between two groups: ST and TT. Postoperative thyroid function (PoTF) changes, including hypothyroidism, euthyro...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | International Journal of Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2015/542641 |
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| author | Tae-Yon Sung Yu-mi Lee Jong Ho Yoon Ki-Wook Chung Suck Joon Hong |
| author_facet | Tae-Yon Sung Yu-mi Lee Jong Ho Yoon Ki-Wook Chung Suck Joon Hong |
| author_sort | Tae-Yon Sung |
| collection | DOAJ |
| description | The present study compared the long-term outcome of subtotal thyroidectomy (ST) to that of total thyroidectomy (TT) in Graves’ disease (GD). Patients with GD requiring surgery were divided between two groups: ST and TT. Postoperative thyroid function (PoTF) changes, including hypothyroidism, euthyroidism, and hyperthyroidism, and surgical complications were analyzed 3 months and 2 years after surgery. During the study period, 350 GD patients underwent surgery, of whom 254 underwent ST and 96 underwent TT. In the ST group, the rates of hypothyroidism, euthyroidism, and hyperthyroidism were 92.5%, 6.7%, and 0.4%, respectively, after 3 months, and 86.1%, 8.6%, and 5.3%, respectively, after 2 years. No difference in the rate of surgical complication was observed between the ST and TT groups (p=0.089). Most of the ST patients showed hypothyroidism after surgery, and euthyroidism was rare. The long-term outcome of ST included noticeable PoTF changes and recurrence of GD. These results suggest that TT should be considered as a treatment option in GD requiring surgery. |
| format | Article |
| id | doaj-art-e5f561b262de466ca5af6ab42750796a |
| institution | Kabale University |
| issn | 1687-8337 1687-8345 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
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| series | International Journal of Endocrinology |
| spelling | doaj-art-e5f561b262de466ca5af6ab42750796a2025-02-03T01:10:59ZengWileyInternational Journal of Endocrinology1687-83371687-83452015-01-01201510.1155/2015/542641542641Long-Term Effect of Surgery in Graves’ Disease: 20 Years Experience in a Single InstitutionTae-Yon Sung0Yu-mi Lee1Jong Ho Yoon2Ki-Wook Chung3Suck Joon Hong4Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul 138-736, Republic of KoreaDepartment of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul 138-736, Republic of KoreaDepartment of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul 138-736, Republic of KoreaDepartment of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul 138-736, Republic of KoreaDepartment of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul 138-736, Republic of KoreaThe present study compared the long-term outcome of subtotal thyroidectomy (ST) to that of total thyroidectomy (TT) in Graves’ disease (GD). Patients with GD requiring surgery were divided between two groups: ST and TT. Postoperative thyroid function (PoTF) changes, including hypothyroidism, euthyroidism, and hyperthyroidism, and surgical complications were analyzed 3 months and 2 years after surgery. During the study period, 350 GD patients underwent surgery, of whom 254 underwent ST and 96 underwent TT. In the ST group, the rates of hypothyroidism, euthyroidism, and hyperthyroidism were 92.5%, 6.7%, and 0.4%, respectively, after 3 months, and 86.1%, 8.6%, and 5.3%, respectively, after 2 years. No difference in the rate of surgical complication was observed between the ST and TT groups (p=0.089). Most of the ST patients showed hypothyroidism after surgery, and euthyroidism was rare. The long-term outcome of ST included noticeable PoTF changes and recurrence of GD. These results suggest that TT should be considered as a treatment option in GD requiring surgery.http://dx.doi.org/10.1155/2015/542641 |
| spellingShingle | Tae-Yon Sung Yu-mi Lee Jong Ho Yoon Ki-Wook Chung Suck Joon Hong Long-Term Effect of Surgery in Graves’ Disease: 20 Years Experience in a Single Institution International Journal of Endocrinology |
| title | Long-Term Effect of Surgery in Graves’ Disease: 20 Years Experience in a Single Institution |
| title_full | Long-Term Effect of Surgery in Graves’ Disease: 20 Years Experience in a Single Institution |
| title_fullStr | Long-Term Effect of Surgery in Graves’ Disease: 20 Years Experience in a Single Institution |
| title_full_unstemmed | Long-Term Effect of Surgery in Graves’ Disease: 20 Years Experience in a Single Institution |
| title_short | Long-Term Effect of Surgery in Graves’ Disease: 20 Years Experience in a Single Institution |
| title_sort | long term effect of surgery in graves disease 20 years experience in a single institution |
| url | http://dx.doi.org/10.1155/2015/542641 |
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