A second-generation molecular clamp stabilised bivalent candidate vaccine for protection against diseases caused by respiratory syncytial virus and human metapneumovirus.

A second-generation molecular clamp stabilised bivalent candidate vaccine for protection against diseases caused by respiratory syncytial virus and human metapneumovirus.

Respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) are two medically important causes of respiratory tract infections and diseases. After more than five decades of research and development, vaccines have recently been approved for the prevention of lower respiratory tract disease cau...

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Main Authors: Andrew Young, Sharada Kolekar, Carlos Alvarez Mendoza, Noushin Jaberolansar, Naphak Modhiran, Tim Webb, Robert McCuaig, Varsha Kommajosyula, Nicolas Tardiota, Quimbe Dy, Alberto A Amarilla, Rhiannon L Dalrymple, Marianne Gillard, Julie L Dutton, Juana Magdalena, Frank Vandendriessche, Jean Smal, Paul R Young, Daniel Watterson, Emmanuel J Hanon, Keith J Chappell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-07-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1013312
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