Isotemporal substitution of sedentary time with physical activity and sleeping time: associations with body composition among individuals with prediabetes

AimTo assess the association between physical activity (PA), sedentary time (ST), and sleep with body composition, and to explore the effects of reallocating ST to PA or sleep on body composition in individuals with prediabetes and overweight/obesity.Material, methods and resultsBaseline data from t...

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Main Authors: M. Torres-Carballo, A. M. Galmes-Panades, M. Arias-Fernández, A. Huguet-Torres, M. Abbate, S. Fresneda, C. Sánchez-Rodríguez, A. M. Yañez, M. Bennasar-Veny
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Sports and Active Living
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Online Access:https://www.frontiersin.org/articles/10.3389/fspor.2025.1579962/full
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author M. Torres-Carballo
M. Torres-Carballo
A. M. Galmes-Panades
A. M. Galmes-Panades
A. M. Galmes-Panades
M. Arias-Fernández
M. Arias-Fernández
M. Arias-Fernández
A. Huguet-Torres
A. Huguet-Torres
M. Abbate
M. Abbate
S. Fresneda
S. Fresneda
S. Fresneda
C. Sánchez-Rodríguez
C. Sánchez-Rodríguez
A. M. Yañez
A. M. Yañez
A. M. Yañez
A. M. Yañez
M. Bennasar-Veny
M. Bennasar-Veny
M. Bennasar-Veny
M. Bennasar-Veny
author_facet M. Torres-Carballo
M. Torres-Carballo
A. M. Galmes-Panades
A. M. Galmes-Panades
A. M. Galmes-Panades
M. Arias-Fernández
M. Arias-Fernández
M. Arias-Fernández
A. Huguet-Torres
A. Huguet-Torres
M. Abbate
M. Abbate
S. Fresneda
S. Fresneda
S. Fresneda
C. Sánchez-Rodríguez
C. Sánchez-Rodríguez
A. M. Yañez
A. M. Yañez
A. M. Yañez
A. M. Yañez
M. Bennasar-Veny
M. Bennasar-Veny
M. Bennasar-Veny
M. Bennasar-Veny
author_sort M. Torres-Carballo
collection DOAJ
description AimTo assess the association between physical activity (PA), sedentary time (ST), and sleep with body composition, and to explore the effects of reallocating ST to PA or sleep on body composition in individuals with prediabetes and overweight/obesity.Material, methods and resultsBaseline data from the PREDIPHONE trial, including 159 participants (mean age 59.6 years) with prediabetes (Fasting Plasma Glucose 100–125 mg/dl) and overweight/obesity (Body Mass Index 27–40 kg/m²), were analyzed. Body composition was assessed via bioelectrical impedance, while PA, ST, and sleep were measured with accelerometry. Linear regression and isotemporal substitution models evaluated associations. Increased ST was positively associated with body fat mass (kg) (β = 0.016; CI 95%: 0.003–0.030), body fat mass (%) (β = 0.009; 0.001–0.018), and visceral adipose tissue (β = 0.005; 0.001–0.010). Moderate-to-vigorous PA (MVPA) was negatively associated with body fat mass (kg) [β = −0.031; 0.055- (−0.008)], body fat mass (%) [β = −0.017; −0.032-(−0.003)], and Visceral adipose tissue [β = −0.009; −0.02-(−0.002)]. Replacing ST with MVPA was linked to lower Visceral adipose tissue [β = −0.012; −0.024-(−0.001)] and body fat mass (kg) [β = −0.039; −0.074-(−0.006)], but not with lean mass. No significant associations were found when substituting ST with light PA or sleep.DiscussionIn individuals with prediabetes and overweight/obesity, replacing ST with MVPA could reduce body fat and VAT but not increases lean mass.
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spelling doaj-art-e5ca754baca446d2aa6b7cc024ca6c4c2025-08-20T02:25:45ZengFrontiers Media S.A.Frontiers in Sports and Active Living2624-93672025-04-01710.3389/fspor.2025.15799621579962Isotemporal substitution of sedentary time with physical activity and sleeping time: associations with body composition among individuals with prediabetesM. Torres-Carballo0M. Torres-Carballo1A. M. Galmes-Panades2A. M. Galmes-Panades3A. M. Galmes-Panades4M. Arias-Fernández5M. Arias-Fernández6M. Arias-Fernández7A. Huguet-Torres8A. Huguet-Torres9M. Abbate10M. Abbate11S. Fresneda12S. Fresneda13S. Fresneda14C. Sánchez-Rodríguez15C. Sánchez-Rodríguez16A. M. Yañez17A. M. Yañez18A. M. Yañez19A. M. Yañez20M. Bennasar-Veny21M. Bennasar-Veny22M. Bennasar-Veny23M. Bennasar-Veny24Research Group on Global Health, University of Balearic Islands, Palma, SpainPrimary Care of Mallorca, Public Health Service of the Balearic Islands, Palma, SpainResearch Group on Nursing, Community & Global Health, Health Research Institute of the Balearic Islands (IdISBa), Palma, SpainCIBER of Physiopathology of Obesity and Nutrition (CIBEROBN), Instituto de Salud Carlos III, Madrid, SpainPhysical Activity and Sport Sciences Research Group (GICAFE), Institute for Educational Research and Innovation, University of the Balearic Islands, Palma, SpainResearch Group on Global Health, University of Balearic Islands, Palma, SpainResearch Group on Nursing, Community & Global Health, Health Research Institute of the Balearic Islands (IdISBa), Palma, SpainNursing and Physiotherapy Department, University of the Balearic Islands, Palma, SpainResearch Group on Global Health, University of Balearic Islands, Palma, SpainNursing and Physiotherapy Department, University of the Balearic Islands, Palma, SpainResearch Group on Global Health, University of Balearic Islands, Palma, SpainResearch Group on Nursing, Community & Global Health, Health Research Institute of the Balearic Islands (IdISBa), Palma, SpainResearch Group on Global Health, University of Balearic Islands, Palma, SpainResearch Group on Nursing, Community & Global Health, Health Research Institute of the Balearic Islands (IdISBa), Palma, SpainNursing and Physiotherapy Department, University of the Balearic Islands, Palma, SpainResearch Group on Global Health, University of Balearic Islands, Palma, SpainHospital Sant Joan de Deu, Palma, SpainResearch Group on Global Health, University of Balearic Islands, Palma, SpainResearch Group on Nursing, Community & Global Health, Health Research Institute of the Balearic Islands (IdISBa), Palma, SpainNursing and Physiotherapy Department, University of the Balearic Islands, Palma, SpainNetwork for Research on Chronicity, Primary Care, and Health Promotion (RICAPPS), Palma, SpainResearch Group on Global Health, University of Balearic Islands, Palma, SpainResearch Group on Nursing, Community & Global Health, Health Research Institute of the Balearic Islands (IdISBa), Palma, SpainNursing and Physiotherapy Department, University of the Balearic Islands, Palma, SpainCentre for Biomedical Research Network (CIBER) in Epidemiology and Public Health (CIBERESP), Madrid, SpainAimTo assess the association between physical activity (PA), sedentary time (ST), and sleep with body composition, and to explore the effects of reallocating ST to PA or sleep on body composition in individuals with prediabetes and overweight/obesity.Material, methods and resultsBaseline data from the PREDIPHONE trial, including 159 participants (mean age 59.6 years) with prediabetes (Fasting Plasma Glucose 100–125 mg/dl) and overweight/obesity (Body Mass Index 27–40 kg/m²), were analyzed. Body composition was assessed via bioelectrical impedance, while PA, ST, and sleep were measured with accelerometry. Linear regression and isotemporal substitution models evaluated associations. Increased ST was positively associated with body fat mass (kg) (β = 0.016; CI 95%: 0.003–0.030), body fat mass (%) (β = 0.009; 0.001–0.018), and visceral adipose tissue (β = 0.005; 0.001–0.010). Moderate-to-vigorous PA (MVPA) was negatively associated with body fat mass (kg) [β = −0.031; 0.055- (−0.008)], body fat mass (%) [β = −0.017; −0.032-(−0.003)], and Visceral adipose tissue [β = −0.009; −0.02-(−0.002)]. Replacing ST with MVPA was linked to lower Visceral adipose tissue [β = −0.012; −0.024-(−0.001)] and body fat mass (kg) [β = −0.039; −0.074-(−0.006)], but not with lean mass. No significant associations were found when substituting ST with light PA or sleep.DiscussionIn individuals with prediabetes and overweight/obesity, replacing ST with MVPA could reduce body fat and VAT but not increases lean mass.https://www.frontiersin.org/articles/10.3389/fspor.2025.1579962/fullbody compositionvisceral adipose tissuephysical activitysedentary timeobesityprediabetes
spellingShingle M. Torres-Carballo
M. Torres-Carballo
A. M. Galmes-Panades
A. M. Galmes-Panades
A. M. Galmes-Panades
M. Arias-Fernández
M. Arias-Fernández
M. Arias-Fernández
A. Huguet-Torres
A. Huguet-Torres
M. Abbate
M. Abbate
S. Fresneda
S. Fresneda
S. Fresneda
C. Sánchez-Rodríguez
C. Sánchez-Rodríguez
A. M. Yañez
A. M. Yañez
A. M. Yañez
A. M. Yañez
M. Bennasar-Veny
M. Bennasar-Veny
M. Bennasar-Veny
M. Bennasar-Veny
Isotemporal substitution of sedentary time with physical activity and sleeping time: associations with body composition among individuals with prediabetes
Frontiers in Sports and Active Living
body composition
visceral adipose tissue
physical activity
sedentary time
obesity
prediabetes
title Isotemporal substitution of sedentary time with physical activity and sleeping time: associations with body composition among individuals with prediabetes
title_full Isotemporal substitution of sedentary time with physical activity and sleeping time: associations with body composition among individuals with prediabetes
title_fullStr Isotemporal substitution of sedentary time with physical activity and sleeping time: associations with body composition among individuals with prediabetes
title_full_unstemmed Isotemporal substitution of sedentary time with physical activity and sleeping time: associations with body composition among individuals with prediabetes
title_short Isotemporal substitution of sedentary time with physical activity and sleeping time: associations with body composition among individuals with prediabetes
title_sort isotemporal substitution of sedentary time with physical activity and sleeping time associations with body composition among individuals with prediabetes
topic body composition
visceral adipose tissue
physical activity
sedentary time
obesity
prediabetes
url https://www.frontiersin.org/articles/10.3389/fspor.2025.1579962/full
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