Information counselling during treatment with ototoxic medications for TB: a call to action
The introduction of bedaquiline (BDQ) has reduced the reliance on ototoxic drugs (e.g., aminoglycosides) for drug-resistant TB (DR-TB). This has significantly reduced ototoxic symptoms, such as tinnitus and dizziness, which often precede irreversible hearing loss. However, aminoglycosides remain ess...
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| Language: | English |
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The Union
2025-03-01
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| Series: | Public Health Action |
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| author | K. Khoza-Shangase S.M. Arendse |
| author_facet | K. Khoza-Shangase S.M. Arendse |
| author_sort | K. Khoza-Shangase |
| collection | DOAJ |
| description | The introduction of bedaquiline (BDQ) has reduced the reliance on ototoxic drugs (e.g., aminoglycosides) for drug-resistant TB (DR-TB). This has significantly reduced ototoxic symptoms, such as tinnitus and dizziness, which often precede irreversible hearing loss. However, aminoglycosides remain essential for some extensively drug-resistant individuals with TB (XDR-TB) who are resistant to BDQ. In South Africa, there is a lack of adequate awareness of the potential ototoxic effects of aminoglycosides. The increasing prevalence of XDR-TB has, therefore, intensified the need for comprehensive information counselling. We call for a proactive role for audiologists in providing early, structured information counselling for these individuals. |
| format | Article |
| id | doaj-art-e5c67e8fd411432ebd9eee1a85b59c9e |
| institution | OA Journals |
| issn | 2220-8372 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | The Union |
| record_format | Article |
| series | Public Health Action |
| spelling | doaj-art-e5c67e8fd411432ebd9eee1a85b59c9e2025-08-20T02:14:39ZengThe UnionPublic Health Action2220-83722025-03-011511310.5588/pha.24.00531Information counselling during treatment with ototoxic medications for TB: a call to actionK. Khoza-ShangaseS.M. ArendseThe introduction of bedaquiline (BDQ) has reduced the reliance on ototoxic drugs (e.g., aminoglycosides) for drug-resistant TB (DR-TB). This has significantly reduced ototoxic symptoms, such as tinnitus and dizziness, which often precede irreversible hearing loss. However, aminoglycosides remain essential for some extensively drug-resistant individuals with TB (XDR-TB) who are resistant to BDQ. In South Africa, there is a lack of adequate awareness of the potential ototoxic effects of aminoglycosides. The increasing prevalence of XDR-TB has, therefore, intensified the need for comprehensive information counselling. We call for a proactive role for audiologists in providing early, structured information counselling for these individuals.https://www.ingentaconnect.com/contentone/iuatld/pha/2025/00000015/00000001/art00001ototoxicitytuberculosisbedaquilineaminoglycosidesaudiologydr-tbxdr-tbsouth africa |
| spellingShingle | K. Khoza-Shangase S.M. Arendse Information counselling during treatment with ototoxic medications for TB: a call to action Public Health Action ototoxicity tuberculosis bedaquiline aminoglycosides audiology dr-tb xdr-tb south africa |
| title | Information counselling during treatment with ototoxic medications for TB: a call to action |
| title_full | Information counselling during treatment with ototoxic medications for TB: a call to action |
| title_fullStr | Information counselling during treatment with ototoxic medications for TB: a call to action |
| title_full_unstemmed | Information counselling during treatment with ototoxic medications for TB: a call to action |
| title_short | Information counselling during treatment with ototoxic medications for TB: a call to action |
| title_sort | information counselling during treatment with ototoxic medications for tb a call to action |
| topic | ototoxicity tuberculosis bedaquiline aminoglycosides audiology dr-tb xdr-tb south africa |
| url | https://www.ingentaconnect.com/contentone/iuatld/pha/2025/00000015/00000001/art00001 |
| work_keys_str_mv | AT kkhozashangase informationcounsellingduringtreatmentwithototoxicmedicationsfortbacalltoaction AT smarendse informationcounsellingduringtreatmentwithototoxicmedicationsfortbacalltoaction |