Information counselling during treatment with ototoxic medications for TB: a call to action
The introduction of bedaquiline (BDQ) has reduced the reliance on ototoxic drugs (e.g., aminoglycosides) for drug-resistant TB (DR-TB). This has significantly reduced ototoxic symptoms, such as tinnitus and dizziness, which often precede irreversible hearing loss. However, aminoglycosides remain ess...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
The Union
2025-03-01
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| Series: | Public Health Action |
| Subjects: | |
| Online Access: | https://www.ingentaconnect.com/contentone/iuatld/pha/2025/00000015/00000001/art00001 |
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| Summary: | The introduction of bedaquiline (BDQ) has reduced the reliance on ototoxic drugs (e.g., aminoglycosides) for drug-resistant TB (DR-TB). This has significantly reduced ototoxic symptoms, such as tinnitus and dizziness, which often precede irreversible hearing loss. However, aminoglycosides remain essential for some extensively drug-resistant individuals with TB (XDR-TB) who are resistant to BDQ. In South Africa, there is a lack of adequate awareness of the potential ototoxic effects of aminoglycosides. The increasing prevalence of XDR-TB has, therefore, intensified the need for comprehensive information counselling. We call for a proactive role for audiologists in providing early, structured information counselling for these individuals. |
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| ISSN: | 2220-8372 |