Scintigraphy assessment of ischemic myocardial viability in patients with post-infarction left ventricular aneurysm

The study included 15patients with coronary heart disease (CHD), post-infarction cardiosclerosis, and chronic left ventricular (LV) aneurysm. All patients underwent interventional myocardial revascularization and Dor aneurysmectomy. Myocardial scintigraphy with 99mTc-MYOVIEW was performed at baselin...

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Main Authors: E. V. Makarova, S. M. Minin, V. I. Chernov, E. V. Krivoshchekov, Yu. V. Lishmanov
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2007-12-01
Series:Российский кардиологический журнал
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Online Access:https://russjcardiol.elpub.ru/jour/article/view/2244
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author E. V. Makarova
S. M. Minin
V. I. Chernov
E. V. Krivoshchekov
Yu. V. Lishmanov
author_facet E. V. Makarova
S. M. Minin
V. I. Chernov
E. V. Krivoshchekov
Yu. V. Lishmanov
author_sort E. V. Makarova
collection DOAJ
description The study included 15patients with coronary heart disease (CHD), post-infarction cardiosclerosis, and chronic left ventricular (LV) aneurysm. All patients underwent interventional myocardial revascularization and Dor aneurysmectomy. Myocardial scintigraphy with 99mTc-MYOVIEW was performed at baseline (during nitroglycerine test and at rest), and 3-4 weeks after revascularization (at rest). According to baseline scintigraphy at rest data, 35 % of the segments were hypoperfused, and in 20 % the agent did not accumulate. After sublingual nitroglycerine administration, hypo- and non-perfused segment percentage reduced to 24 % and 11 %, respectively, after revascularization - to 24 % and 11 %. Single-photon emission computed tomography with 99mTc-MYOVIEW, combined with sublingual nitroglycerin test, identifies viable myocardial zones in post-infarction LV aneurism area and might be used for predicting post-revascularization LV function recovery.
format Article
id doaj-art-e5aef8243e97465f96a3fdffa63704fd
institution Kabale University
issn 1560-4071
2618-7620
language Russian
publishDate 2007-12-01
publisher «FIRMA «SILICEA» LLC
record_format Article
series Российский кардиологический журнал
spelling doaj-art-e5aef8243e97465f96a3fdffa63704fd2025-08-20T03:57:25Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202007-12-010622261996Scintigraphy assessment of ischemic myocardial viability in patients with post-infarction left ventricular aneurysmE. V. Makarova0S. M. Minin1V. I. Chernov2E. V. Krivoshchekov3Yu. V. Lishmanov4Научно-исследовательский институт кардиологии Томского научного центра СО РАМННаучно-исследовательский институт кардиологии Томского научного центра СО РАМННаучно-исследовательский институт кардиологии Томского научного центра СО РАМННаучно-исследовательский институт кардиологии Томского научного центра СО РАМННаучно-исследовательский институт кардиологии Томского научного центра СО РАМНThe study included 15patients with coronary heart disease (CHD), post-infarction cardiosclerosis, and chronic left ventricular (LV) aneurysm. All patients underwent interventional myocardial revascularization and Dor aneurysmectomy. Myocardial scintigraphy with 99mTc-MYOVIEW was performed at baseline (during nitroglycerine test and at rest), and 3-4 weeks after revascularization (at rest). According to baseline scintigraphy at rest data, 35 % of the segments were hypoperfused, and in 20 % the agent did not accumulate. After sublingual nitroglycerine administration, hypo- and non-perfused segment percentage reduced to 24 % and 11 %, respectively, after revascularization - to 24 % and 11 %. Single-photon emission computed tomography with 99mTc-MYOVIEW, combined with sublingual nitroglycerin test, identifies viable myocardial zones in post-infarction LV aneurism area and might be used for predicting post-revascularization LV function recovery.https://russjcardiol.elpub.ru/jour/article/view/2244myocardial perfusionhibernationviabilitycoronary heart diseasenitroglycerin
spellingShingle E. V. Makarova
S. M. Minin
V. I. Chernov
E. V. Krivoshchekov
Yu. V. Lishmanov
Scintigraphy assessment of ischemic myocardial viability in patients with post-infarction left ventricular aneurysm
Российский кардиологический журнал
myocardial perfusion
hibernation
viability
coronary heart disease
nitroglycerin
title Scintigraphy assessment of ischemic myocardial viability in patients with post-infarction left ventricular aneurysm
title_full Scintigraphy assessment of ischemic myocardial viability in patients with post-infarction left ventricular aneurysm
title_fullStr Scintigraphy assessment of ischemic myocardial viability in patients with post-infarction left ventricular aneurysm
title_full_unstemmed Scintigraphy assessment of ischemic myocardial viability in patients with post-infarction left ventricular aneurysm
title_short Scintigraphy assessment of ischemic myocardial viability in patients with post-infarction left ventricular aneurysm
title_sort scintigraphy assessment of ischemic myocardial viability in patients with post infarction left ventricular aneurysm
topic myocardial perfusion
hibernation
viability
coronary heart disease
nitroglycerin
url https://russjcardiol.elpub.ru/jour/article/view/2244
work_keys_str_mv AT evmakarova scintigraphyassessmentofischemicmyocardialviabilityinpatientswithpostinfarctionleftventricularaneurysm
AT smminin scintigraphyassessmentofischemicmyocardialviabilityinpatientswithpostinfarctionleftventricularaneurysm
AT vichernov scintigraphyassessmentofischemicmyocardialviabilityinpatientswithpostinfarctionleftventricularaneurysm
AT evkrivoshchekov scintigraphyassessmentofischemicmyocardialviabilityinpatientswithpostinfarctionleftventricularaneurysm
AT yuvlishmanov scintigraphyassessmentofischemicmyocardialviabilityinpatientswithpostinfarctionleftventricularaneurysm