Markers of Primary Chemoresistance of Epithelial Ascites Cells in Patients with Ovarian Cancer Guidelines for Practitioners

Markers of Primary Chemoresistance of Epithelial Ascites Cells in Patients with Ovarian Cancer Guidelines for Practitioners

Determined the primary chemoresistance markers (expression of genes ERCC1, TOP2a and ABCB1) in epithelial cells of ascites 32 primary patients with verified ovarian cancer using RT-PCR. After standard chemotherapy by the AR scheme (cisplatin+doxoru-bicin), the relapse-free survival of patients was a...

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Bibliographic Details
Main Authors: D. R. Dolgova, T. P. Gening, T. V. Abakumova, S. O. Gening, I. I. Antoneeva, A. B. Pescov, A. Yu. Fedotova
Format: Article
Language:Russian
Published: LLC "Publishing House OKI" 2020-05-01
Series:Антибиотики и Химиотерапия
Subjects:
ovarian cancer
ascites
drug resistance genes
relapse-free survival
Online Access:https://www.antibiotics-chemotherapy.ru/jour/article/view/137
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