The role of peptide hormones (adiponectin, leptin, insulin) in the pathogenesis of atherosclerosis
Currently, cardiovascular diseases (CVD) remain the main problem in the world and in Russia in particular. The study of the causes and progression of atherosclerosis is a critical moment in the fight against CVD. Adipose tissue and processes that occur in it attracts attention in recent years. The i...
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| Format: | Article |
| Language: | English |
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Столичная издательская компания
2015-11-01
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| Series: | Рациональная фармакотерапия в кардиологии |
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| Online Access: | https://www.rpcardio.online/jour/article/view/327 |
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| author | S. A. Smetnev A. N. Meshkov |
| author_facet | S. A. Smetnev A. N. Meshkov |
| author_sort | S. A. Smetnev |
| collection | DOAJ |
| description | Currently, cardiovascular diseases (CVD) remain the main problem in the world and in Russia in particular. The study of the causes and progression of atherosclerosis is a critical moment in the fight against CVD. Adipose tissue and processes that occur in it attracts attention in recent years. The important role of adipose tissue as an endocrine and immune organ is revealed as well as its participation in the development of the inflammatory process. This leads to the development of initial manifestations of atherosclerosis a precursor of many metabolic disorders and CVD. Particular attention causes adipokines regulatory peptide hormones in the adipose tissue, as well as insulin, due to its close relationship with the adipose tissue and especially with adiponectin and leptin. Recent data on the role of adiponectin, leptin and insulin in the pathogenesis of atherosclerosis in order to identify new potential targets among peptide hormones for the treatment of atherosclerosis are presented. |
| format | Article |
| id | doaj-art-e588ec62bbd440f7af8d87a6b0dbf156 |
| institution | Kabale University |
| issn | 1819-6446 2225-3653 |
| language | English |
| publishDate | 2015-11-01 |
| publisher | Столичная издательская компания |
| record_format | Article |
| series | Рациональная фармакотерапия в кардиологии |
| spelling | doaj-art-e588ec62bbd440f7af8d87a6b0dbf1562025-08-23T10:00:18ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532015-11-0111552252810.20996/1819-6446-2015-11-5-522-528327The role of peptide hormones (adiponectin, leptin, insulin) in the pathogenesis of atherosclerosisS. A. Smetnev0A. N. Meshkov1State Research Centre for Preventive Medicine. Petroverigsky per. 10, Moscow, 101990 RussiaState Research Centre for Preventive Medicine. Petroverigsky per. 10, Moscow, 101990 RussiaCurrently, cardiovascular diseases (CVD) remain the main problem in the world and in Russia in particular. The study of the causes and progression of atherosclerosis is a critical moment in the fight against CVD. Adipose tissue and processes that occur in it attracts attention in recent years. The important role of adipose tissue as an endocrine and immune organ is revealed as well as its participation in the development of the inflammatory process. This leads to the development of initial manifestations of atherosclerosis a precursor of many metabolic disorders and CVD. Particular attention causes adipokines regulatory peptide hormones in the adipose tissue, as well as insulin, due to its close relationship with the adipose tissue and especially with adiponectin and leptin. Recent data on the role of adiponectin, leptin and insulin in the pathogenesis of atherosclerosis in order to identify new potential targets among peptide hormones for the treatment of atherosclerosis are presented.https://www.rpcardio.online/jour/article/view/327regulatory peptidesadiponectinleptininsulincardiovascular diseasesfatty tissue |
| spellingShingle | S. A. Smetnev A. N. Meshkov The role of peptide hormones (adiponectin, leptin, insulin) in the pathogenesis of atherosclerosis Рациональная фармакотерапия в кардиологии regulatory peptides adiponectin leptin insulin cardiovascular diseases fatty tissue |
| title | The role of peptide hormones (adiponectin, leptin, insulin) in the pathogenesis of atherosclerosis |
| title_full | The role of peptide hormones (adiponectin, leptin, insulin) in the pathogenesis of atherosclerosis |
| title_fullStr | The role of peptide hormones (adiponectin, leptin, insulin) in the pathogenesis of atherosclerosis |
| title_full_unstemmed | The role of peptide hormones (adiponectin, leptin, insulin) in the pathogenesis of atherosclerosis |
| title_short | The role of peptide hormones (adiponectin, leptin, insulin) in the pathogenesis of atherosclerosis |
| title_sort | role of peptide hormones adiponectin leptin insulin in the pathogenesis of atherosclerosis |
| topic | regulatory peptides adiponectin leptin insulin cardiovascular diseases fatty tissue |
| url | https://www.rpcardio.online/jour/article/view/327 |
| work_keys_str_mv | AT sasmetnev theroleofpeptidehormonesadiponectinleptininsulininthepathogenesisofatherosclerosis AT anmeshkov theroleofpeptidehormonesadiponectinleptininsulininthepathogenesisofatherosclerosis AT sasmetnev roleofpeptidehormonesadiponectinleptininsulininthepathogenesisofatherosclerosis AT anmeshkov roleofpeptidehormonesadiponectinleptininsulininthepathogenesisofatherosclerosis |