METHODOLOGY FOR DATA COLLECTION IN SIMULATED IRRADIATIONS USING MONTE CARLO TECHNIQUES ON DICOM IMAGES FOR X-RAY FLUORESCENCE EMISSIONS LOCALIZATION IN HIGH ATOMIC NUMBER MATERIALS
X-ray Fluorescence Computed Tomography (XFCT) has emerged as a promising modality owing to the availability of high-energy polychromatic X-ray sources in the laboratory. As compared to other modalities, XFCT offers advantages such as easy accessibility, low instrumentation costs, and efficient opera...
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CEILAP-UNIDEF-CONICET-CITEDEF
2024-12-01
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| Series: | Anales (Asociación Física Argentina) |
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| Online Access: | https://anales.fisica.org.ar/index.php/analesafa/article/view/2441/3010 |
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| author | Nicolás E. Martín F. Malano Miguel Sofo Haro M. Valente |
| author_facet | Nicolás E. Martín F. Malano Miguel Sofo Haro M. Valente |
| author_sort | Nicolás E. Martín |
| collection | DOAJ |
| description | X-ray Fluorescence Computed Tomography (XFCT) has emerged as a promising modality owing to the availability of high-energy polychromatic X-ray sources in the laboratory. As compared to other modalities, XFCT offers advantages such as easy accessibility, low instrumentation costs, and efficient operation. This approach allows for simultaneous transmission computed tomography (CT) along with XFCT, providing multimodal/multiplexed in vivo images and expanding applications with metallic probes such as gold nanoparticles (AuNPs). Despite its benefits, CT+XFCT imaging poses challenges, particularly in minimizing X-ray dose. Research into accurate methods for estimating the location of X-ray fluorescence emissions has led to various techniques and developments, applied both experimentally and through simulations.This work introduces an innovative methodology based on X-ray energy dispersion spectrometry, using DICOM images to create probability maps of fluorescence emission locations. We applied this methodology to localize nanoparticles in computer-generated phantoms, demonstrating its feasibility and versatility through Monte Carlo simulations and correlation with micro-tomography. This methodology emerges as a promising tool for obtaining functional information in complex biomedical environments. |
| format | Article |
| id | doaj-art-e586cec6c2f940c0b870b9cddfa56474 |
| institution | Kabale University |
| issn | 1850-1168 |
| language | Spanish |
| publishDate | 2024-12-01 |
| publisher | CEILAP-UNIDEF-CONICET-CITEDEF |
| record_format | Article |
| series | Anales (Asociación Física Argentina) |
| spelling | doaj-art-e586cec6c2f940c0b870b9cddfa564742025-01-22T23:58:26ZspaCEILAP-UNIDEF-CONICET-CITEDEFAnales (Asociación Física Argentina)1850-11682024-12-013549510210.31527/analesafa.2024.35.4.95METHODOLOGY FOR DATA COLLECTION IN SIMULATED IRRADIATIONS USING MONTE CARLO TECHNIQUES ON DICOM IMAGES FOR X-RAY FLUORESCENCE EMISSIONS LOCALIZATION IN HIGH ATOMIC NUMBER MATERIALSNicolás E. Martín0F. Malano1Miguel Sofo Haro2M. Valente31,2,41Instituto de Física Enrique Gaviola, CONICET, FAMAF, UNC, Córdoba, 5000, Argentina2Laboratorio de Investigaciones e Instrumentación en Física Aplicada a la Medicina e Imágenes por Rayos X -LIIFAMIRx⃝, FAMAF,Universidad Nacional de Córdoba, Córdoba, 5000, ArgentinaCentro de Física e Ingeniería en Salud, CFIS &, Depto. de Ciencias Físicas, Universidad de la Frontera, Temuco, 4780000, Chile.1Instituto de Física Enrique Gaviola, CONICET, FAMAF, UNC, Córdoba, 5000, Argentina Argentina3Reactor Nuclear RA0, Comisión Nacional de Energía Atómica.1Instituto de Física Enrique Gaviola, CONICET, FAMAF, UNC, Córdoba, 5000, Argentina 2Laboratorio de Investigaciones e Instrumentación en Física Aplicada a la Medicina e Imágenes por Rayos X -LIIFAMIRx⃝, FAMAF,Universidad Nacional de Córdoba, Córdoba, 5000, Argentina Centro de Física e Ingeniería en Salud, CFIS &, Depto. de Ciencias Físicas, Universidad de la Frontera, Temuco, 4780000, Chile.X-ray Fluorescence Computed Tomography (XFCT) has emerged as a promising modality owing to the availability of high-energy polychromatic X-ray sources in the laboratory. As compared to other modalities, XFCT offers advantages such as easy accessibility, low instrumentation costs, and efficient operation. This approach allows for simultaneous transmission computed tomography (CT) along with XFCT, providing multimodal/multiplexed in vivo images and expanding applications with metallic probes such as gold nanoparticles (AuNPs). Despite its benefits, CT+XFCT imaging poses challenges, particularly in minimizing X-ray dose. Research into accurate methods for estimating the location of X-ray fluorescence emissions has led to various techniques and developments, applied both experimentally and through simulations.This work introduces an innovative methodology based on X-ray energy dispersion spectrometry, using DICOM images to create probability maps of fluorescence emission locations. We applied this methodology to localize nanoparticles in computer-generated phantoms, demonstrating its feasibility and versatility through Monte Carlo simulations and correlation with micro-tomography. This methodology emerges as a promising tool for obtaining functional information in complex biomedical environments.https://anales.fisica.org.ar/index.php/analesafa/article/view/2441/3010monte carloxfctnanoparticles |
| spellingShingle | Nicolás E. Martín F. Malano Miguel Sofo Haro M. Valente METHODOLOGY FOR DATA COLLECTION IN SIMULATED IRRADIATIONS USING MONTE CARLO TECHNIQUES ON DICOM IMAGES FOR X-RAY FLUORESCENCE EMISSIONS LOCALIZATION IN HIGH ATOMIC NUMBER MATERIALS Anales (Asociación Física Argentina) monte carlo xfct nanoparticles |
| title | METHODOLOGY FOR DATA COLLECTION IN SIMULATED IRRADIATIONS USING MONTE CARLO TECHNIQUES ON DICOM IMAGES FOR X-RAY FLUORESCENCE EMISSIONS LOCALIZATION IN HIGH ATOMIC NUMBER MATERIALS |
| title_full | METHODOLOGY FOR DATA COLLECTION IN SIMULATED IRRADIATIONS USING MONTE CARLO TECHNIQUES ON DICOM IMAGES FOR X-RAY FLUORESCENCE EMISSIONS LOCALIZATION IN HIGH ATOMIC NUMBER MATERIALS |
| title_fullStr | METHODOLOGY FOR DATA COLLECTION IN SIMULATED IRRADIATIONS USING MONTE CARLO TECHNIQUES ON DICOM IMAGES FOR X-RAY FLUORESCENCE EMISSIONS LOCALIZATION IN HIGH ATOMIC NUMBER MATERIALS |
| title_full_unstemmed | METHODOLOGY FOR DATA COLLECTION IN SIMULATED IRRADIATIONS USING MONTE CARLO TECHNIQUES ON DICOM IMAGES FOR X-RAY FLUORESCENCE EMISSIONS LOCALIZATION IN HIGH ATOMIC NUMBER MATERIALS |
| title_short | METHODOLOGY FOR DATA COLLECTION IN SIMULATED IRRADIATIONS USING MONTE CARLO TECHNIQUES ON DICOM IMAGES FOR X-RAY FLUORESCENCE EMISSIONS LOCALIZATION IN HIGH ATOMIC NUMBER MATERIALS |
| title_sort | methodology for data collection in simulated irradiations using monte carlo techniques on dicom images for x ray fluorescence emissions localization in high atomic number materials |
| topic | monte carlo xfct nanoparticles |
| url | https://anales.fisica.org.ar/index.php/analesafa/article/view/2441/3010 |
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