Genetic context modulates aging and degeneration in the murine retina

Genetic context modulates aging and degeneration in the murine retina

Abstract Background Age is the principal risk factor for neurodegeneration in both the retina and brain. The retina and brain share many biological properties; thus, insights into retinal aging and degeneration may shed light onto similar processes in the brain. Genetic makeup strongly influences su...

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Bibliographic Details
Main Authors: Olivia J. Marola, Michael MacLean, Travis L. Cossette, Cory A. Diemler, Amanda A. Hewes, Alaina M. Reagan, Jonathan Nyandu Kanyinda, Daniel A. Skelly, Gareth R. Howell
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Molecular Neurodegeneration
Subjects:
WSB
NZO
Diabetic retinopathy
Retinitis pigmentosa
Genetic diversity
Aging
Online Access:https://doi.org/10.1186/s13024-025-00800-9
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