MiR-18a-LncRNA NONRATG-022419 pairs targeted PRG-1 regulates diabetic induced cognitive impairment by regulating NGF\BDNF-Trkb signaling pathway

MiR-18a-LncRNA NONRATG-022419 pairs targeted PRG-1 regulates diabetic induced cognitive impairment by regulating NGF\BDNF-Trkb signaling pathway

Abstract Background Diabetic encephalopathy (DE) is considered as one of the complications of diabetes,which is associated with cognitive impairment in the pathological process of development. Up to now, phospholipid phosphatase related 4 (Plppr4), also known as plasticity related gene 1 (PRG-1) has...

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Bibliographic Details
Main Authors: Qiong Xiang, Hu Lin, Jia-Sheng Tao, Chuan-Jun Fu, Li-Ni Liu, Jing Deng, Xian-Hui Li
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Proteome Science
Subjects:
Diabetic encephalopathy
Diabetic induced cognitive dysfunction
Hippocampus
Synaptic plasticity regulation
Type I spiral ganglion neurons
PRG-1
Online Access:https://doi.org/10.1186/s12953-025-00239-2
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