Anti-SARS-CoV-2 Antibody Level among Renal Transplant Recipients: A Case Report from Nepal
Globally, SARS-CoV-2 has caused significant public health burden, mainly in patients with underlying comorbidities including both communicable and noncommunicable diseases. Solid organ transplant recipients under immunesupressive medication are also amongst the high risk group. There is only sparse...
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Case Reports in Urology |
| Online Access: | http://dx.doi.org/10.1155/2022/2889501 |
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| author | Kamal Ranabhat Bhuvan Saud Saroj Adhikari Suraj Bhattarai Rojan Adhikari Bhoj Raj Luitel Mahesh Raj Sigdel |
| author_facet | Kamal Ranabhat Bhuvan Saud Saroj Adhikari Suraj Bhattarai Rojan Adhikari Bhoj Raj Luitel Mahesh Raj Sigdel |
| author_sort | Kamal Ranabhat |
| collection | DOAJ |
| description | Globally, SARS-CoV-2 has caused significant public health burden, mainly in patients with underlying comorbidities including both communicable and noncommunicable diseases. Solid organ transplant recipients under immunesupressive medication are also amongst the high risk group. There is only sparse data on immunity against SARS-CoV-2 infection among renal transplant recipients. In this case report, we present the level of anti-SARS-CoV-2 antibody of three kidney transplant recipients after vaccination against COVID-19 virus. All three cases had received two doses of Oxford-AstraZeneca COVID-19 vaccine AZD1222 (ChAdOx1). Serological analysis showed protective level of circulating antibodies in the blood of all three cases. Although two out of three patients in the study acquired COVID-19 infection after immunization, they recovered with mild clinical course. Hence, we conclude that despite immune-suppressed status of transplant recipients, COVID-19 vaccination could protect them against severe illness. |
| format | Article |
| id | doaj-art-e518fcb5c0094d08bf8def35af20ffac |
| institution | Kabale University |
| issn | 2090-6978 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Urology |
| spelling | doaj-art-e518fcb5c0094d08bf8def35af20ffac2025-02-03T01:04:45ZengWileyCase Reports in Urology2090-69782022-01-01202210.1155/2022/2889501Anti-SARS-CoV-2 Antibody Level among Renal Transplant Recipients: A Case Report from NepalKamal Ranabhat0Bhuvan Saud1Saroj Adhikari2Suraj Bhattarai3Rojan Adhikari4Bhoj Raj Luitel5Mahesh Raj Sigdel6Institue of MedicineDepartment of Medical Laboratory TechnologyNational Trauma CenterGlobal Institute for Interdisciplinary StudiesShahid Dharma Bhakta National Transplant CenterInstitue of MedicineInstitue of MedicineGlobally, SARS-CoV-2 has caused significant public health burden, mainly in patients with underlying comorbidities including both communicable and noncommunicable diseases. Solid organ transplant recipients under immunesupressive medication are also amongst the high risk group. There is only sparse data on immunity against SARS-CoV-2 infection among renal transplant recipients. In this case report, we present the level of anti-SARS-CoV-2 antibody of three kidney transplant recipients after vaccination against COVID-19 virus. All three cases had received two doses of Oxford-AstraZeneca COVID-19 vaccine AZD1222 (ChAdOx1). Serological analysis showed protective level of circulating antibodies in the blood of all three cases. Although two out of three patients in the study acquired COVID-19 infection after immunization, they recovered with mild clinical course. Hence, we conclude that despite immune-suppressed status of transplant recipients, COVID-19 vaccination could protect them against severe illness.http://dx.doi.org/10.1155/2022/2889501 |
| spellingShingle | Kamal Ranabhat Bhuvan Saud Saroj Adhikari Suraj Bhattarai Rojan Adhikari Bhoj Raj Luitel Mahesh Raj Sigdel Anti-SARS-CoV-2 Antibody Level among Renal Transplant Recipients: A Case Report from Nepal Case Reports in Urology |
| title | Anti-SARS-CoV-2 Antibody Level among Renal Transplant Recipients: A Case Report from Nepal |
| title_full | Anti-SARS-CoV-2 Antibody Level among Renal Transplant Recipients: A Case Report from Nepal |
| title_fullStr | Anti-SARS-CoV-2 Antibody Level among Renal Transplant Recipients: A Case Report from Nepal |
| title_full_unstemmed | Anti-SARS-CoV-2 Antibody Level among Renal Transplant Recipients: A Case Report from Nepal |
| title_short | Anti-SARS-CoV-2 Antibody Level among Renal Transplant Recipients: A Case Report from Nepal |
| title_sort | anti sars cov 2 antibody level among renal transplant recipients a case report from nepal |
| url | http://dx.doi.org/10.1155/2022/2889501 |
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