Mechanisms and Therapeutic Potential of GPX4 in Pain Modulation

Mechanisms and Therapeutic Potential of GPX4 in Pain Modulation

Abstract Pain, a complex symptom encompassing both sensory and emotional dimensions, constitutes a significant global public health issue. Oxidative stress is a pivotal factor in the complex pathophysiology of pain, with glutathione peroxidase 4 (GPX4) recognized as a crucial antioxidant enzyme invo...

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Bibliographic Details
Main Authors: Shiwen Fan, Kaixin Wang, Tianhao Zhang, Daling Deng, Jiwei Shen, Bowen Zhao, Daan Fu, Xiangdong Chen
Format: Article
Language:English
Published: Adis, Springer Healthcare 2024-11-01
Series:Pain and Therapy
Subjects:
Glutathione peroxidase 4
Oxidative stress
Mechanisms
Pain regulation
Online Access:https://doi.org/10.1007/s40122-024-00673-8
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