Microglia are required for developmental specification of AgRP innervation in the hypothalamus of offspring exposed to maternal high-fat diet during lactation

Microglia are required for developmental specification of AgRP innervation in the hypothalamus of offspring exposed to maternal high-fat diet during lactation

Agouti-related peptide (AgRP) neurons in the arcuate nucleus of the hypothalamus respond to multiple metabolic signals and distribute neuroendocrine information to other brain regions such as the paraventricular hypothalamic nucleus (PVH), which plays a central role in metabolic homeostasis. Neural...

Full description

Saved in:
Bibliographic Details
Main Authors: Haley N Mendoza-Romero, Jessica E Biddinger, Michelle N Bedenbaugh, Richard Simerly
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-06-01
Series:eLife
Subjects:
microglia
AgRP
hypothalamus
Online Access:https://elifesciences.org/articles/101391
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items