A Review of Botany, Phytochemistry, and Biological Activities of Eight <i>Salvia</i> Species Widespread in Kazakhstan

The aim of this review is to provide a comprehensive overview of the botany, phytochemistry, and biological activities of eight <i>Salvia</i> species, namely <i>Salvia aethiopis</i> L., <i>S</i>. <i>sclarea</i> L., <i>S</i>. <i>dumeto...

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Main Authors: Yana Levaya, Gayane Atazhanova, Vika Gabe, Karakoz Badekova
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Molecules
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Online Access:https://www.mdpi.com/1420-3049/30/5/1142
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author Yana Levaya
Gayane Atazhanova
Vika Gabe
Karakoz Badekova
author_facet Yana Levaya
Gayane Atazhanova
Vika Gabe
Karakoz Badekova
author_sort Yana Levaya
collection DOAJ
description The aim of this review is to provide a comprehensive overview of the botany, phytochemistry, and biological activities of eight <i>Salvia</i> species, namely <i>Salvia aethiopis</i> L., <i>S</i>. <i>sclarea</i> L., <i>S</i>. <i>dumetorum</i> Andrz. ex Besser, <i>S</i>. <i>deserta</i> Schang., <i>S</i>. <i>trautvetteri</i> Rgl., <i>S</i>. <i>macrosiphon</i> Boiss., <i>S</i>. <i>virgata</i> Jacq., and <i>S</i>. <i>verticillata</i> L., which are widespread in Kazakhstan. The genus <i>Salvia</i> is renowned for its diverse medicinal properties, and these species are no exception, contributing to the rich natural pharmacopoeia of the region. The botanical characteristics of these species, including their morphological features, distribution, and ecological adaptations, are discussed. The present review also explores the phytochemical composition of these plants, focusing on bioactive compounds such as terpenoids, flavonoids, alkaloids, and phenolic acids, which are responsible for their medicinal potential. Biological activities including antimicrobial, antioxidant, anti-inflammatory, antidiabetic, and neuroprotective effects are evaluated based on available in vitro and in vivo studies. In addition, the review highlights the traditional uses of these species in local medicine and suggests avenues for future research to further elucidate their pharmacological potential. This synthesis provides valuable insights into the medicinal importance of these <i>Salvia</i> species in Kazakhstan and supports their continued exploration for therapeutic applications.
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spelling doaj-art-e4eabd7129fd410fb952940e481eb7322025-08-20T02:52:35ZengMDPI AGMolecules1420-30492025-03-01305114210.3390/molecules30051142A Review of Botany, Phytochemistry, and Biological Activities of Eight <i>Salvia</i> Species Widespread in KazakhstanYana Levaya0Gayane Atazhanova1Vika Gabe2Karakoz Badekova3School of Pharmacy, Karaganda Medical University, Gogol Street, 40, Karaganda 100017, KazakhstanSchool of Pharmacy, Karaganda Medical University, Gogol Street, 40, Karaganda 100017, KazakhstanDepartment of Physiology, Biochemistry, Microbiology and Laboratory Medicine, Institute of Biomedical Sciences, Faculty of Medicine, Vilnius University, 03101 Vilnius, LithuaniaSchool of Pharmacy, Karaganda Medical University, Gogol Street, 40, Karaganda 100017, KazakhstanThe aim of this review is to provide a comprehensive overview of the botany, phytochemistry, and biological activities of eight <i>Salvia</i> species, namely <i>Salvia aethiopis</i> L., <i>S</i>. <i>sclarea</i> L., <i>S</i>. <i>dumetorum</i> Andrz. ex Besser, <i>S</i>. <i>deserta</i> Schang., <i>S</i>. <i>trautvetteri</i> Rgl., <i>S</i>. <i>macrosiphon</i> Boiss., <i>S</i>. <i>virgata</i> Jacq., and <i>S</i>. <i>verticillata</i> L., which are widespread in Kazakhstan. The genus <i>Salvia</i> is renowned for its diverse medicinal properties, and these species are no exception, contributing to the rich natural pharmacopoeia of the region. The botanical characteristics of these species, including their morphological features, distribution, and ecological adaptations, are discussed. The present review also explores the phytochemical composition of these plants, focusing on bioactive compounds such as terpenoids, flavonoids, alkaloids, and phenolic acids, which are responsible for their medicinal potential. Biological activities including antimicrobial, antioxidant, anti-inflammatory, antidiabetic, and neuroprotective effects are evaluated based on available in vitro and in vivo studies. In addition, the review highlights the traditional uses of these species in local medicine and suggests avenues for future research to further elucidate their pharmacological potential. This synthesis provides valuable insights into the medicinal importance of these <i>Salvia</i> species in Kazakhstan and supports their continued exploration for therapeutic applications.https://www.mdpi.com/1420-3049/30/5/1142botanyphytochemistrybiological activitiestraditional medicinemedicinal plantsbioactive compounds
spellingShingle Yana Levaya
Gayane Atazhanova
Vika Gabe
Karakoz Badekova
A Review of Botany, Phytochemistry, and Biological Activities of Eight <i>Salvia</i> Species Widespread in Kazakhstan
Molecules
botany
phytochemistry
biological activities
traditional medicine
medicinal plants
bioactive compounds
title A Review of Botany, Phytochemistry, and Biological Activities of Eight <i>Salvia</i> Species Widespread in Kazakhstan
title_full A Review of Botany, Phytochemistry, and Biological Activities of Eight <i>Salvia</i> Species Widespread in Kazakhstan
title_fullStr A Review of Botany, Phytochemistry, and Biological Activities of Eight <i>Salvia</i> Species Widespread in Kazakhstan
title_full_unstemmed A Review of Botany, Phytochemistry, and Biological Activities of Eight <i>Salvia</i> Species Widespread in Kazakhstan
title_short A Review of Botany, Phytochemistry, and Biological Activities of Eight <i>Salvia</i> Species Widespread in Kazakhstan
title_sort review of botany phytochemistry and biological activities of eight i salvia i species widespread in kazakhstan
topic botany
phytochemistry
biological activities
traditional medicine
medicinal plants
bioactive compounds
url https://www.mdpi.com/1420-3049/30/5/1142
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