A Rare Case of Hypercalcemia from Mediastinal Ectopic Hyperparathyroidism
Hypercalcemia is frequently attributed to primary hyperparathyroidism, commonly a result of parathyroid adenomas. Ectopic hyperparathyroidism is characterized by hyperfunctioning parathyroid tissue located outside of expected anatomical locations of endocrine tissue. In this report, we present a rar...
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MDPI AG
2025-05-01
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| Series: | Journal of Cardiovascular Development and Disease |
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| Online Access: | https://www.mdpi.com/2308-3425/12/6/201 |
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| author | Nasrin Dhapa Lamar Alocozy Rumana Khan |
| author_facet | Nasrin Dhapa Lamar Alocozy Rumana Khan |
| author_sort | Nasrin Dhapa |
| collection | DOAJ |
| description | Hypercalcemia is frequently attributed to primary hyperparathyroidism, commonly a result of parathyroid adenomas. Ectopic hyperparathyroidism is characterized by hyperfunctioning parathyroid tissue located outside of expected anatomical locations of endocrine tissue. In this report, we present a rare case of hypercalcemia secondary to a mediastinal ectopic parathyroid adenoma, located between the left atrium and pulmonary artery. Given the unique location of the ectopic gland, diagnosis was delayed with additional complications that followed due to difficulty accessing the gland surgically. Despite this, urgent surgical removal of the ectopic gland allowed for remarkable improvement in presenting symptoms. This clinical case highlights diagnostic and therapeutic challenges that present a unique situation worthy of clinical discussion. |
| format | Article |
| id | doaj-art-e4e3166a4f8b4bd8abe9cf62dae8a7f2 |
| institution | Kabale University |
| issn | 2308-3425 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Cardiovascular Development and Disease |
| spelling | doaj-art-e4e3166a4f8b4bd8abe9cf62dae8a7f22025-08-20T03:27:22ZengMDPI AGJournal of Cardiovascular Development and Disease2308-34252025-05-0112620110.3390/jcdd12060201A Rare Case of Hypercalcemia from Mediastinal Ectopic HyperparathyroidismNasrin Dhapa0Lamar Alocozy1Rumana Khan2Sutter Roseville Medical Center, Graduate Medical Education, Roseville, CA 95661, USASutter Roseville Medical Center, Graduate Medical Education, Roseville, CA 95661, USASutter Roseville Medical Center, Graduate Medical Education, Roseville, CA 95661, USAHypercalcemia is frequently attributed to primary hyperparathyroidism, commonly a result of parathyroid adenomas. Ectopic hyperparathyroidism is characterized by hyperfunctioning parathyroid tissue located outside of expected anatomical locations of endocrine tissue. In this report, we present a rare case of hypercalcemia secondary to a mediastinal ectopic parathyroid adenoma, located between the left atrium and pulmonary artery. Given the unique location of the ectopic gland, diagnosis was delayed with additional complications that followed due to difficulty accessing the gland surgically. Despite this, urgent surgical removal of the ectopic gland allowed for remarkable improvement in presenting symptoms. This clinical case highlights diagnostic and therapeutic challenges that present a unique situation worthy of clinical discussion.https://www.mdpi.com/2308-3425/12/6/201primary hyperparathyroidismhypercalcemiaectopic diseaseendocrinology |
| spellingShingle | Nasrin Dhapa Lamar Alocozy Rumana Khan A Rare Case of Hypercalcemia from Mediastinal Ectopic Hyperparathyroidism Journal of Cardiovascular Development and Disease primary hyperparathyroidism hypercalcemia ectopic disease endocrinology |
| title | A Rare Case of Hypercalcemia from Mediastinal Ectopic Hyperparathyroidism |
| title_full | A Rare Case of Hypercalcemia from Mediastinal Ectopic Hyperparathyroidism |
| title_fullStr | A Rare Case of Hypercalcemia from Mediastinal Ectopic Hyperparathyroidism |
| title_full_unstemmed | A Rare Case of Hypercalcemia from Mediastinal Ectopic Hyperparathyroidism |
| title_short | A Rare Case of Hypercalcemia from Mediastinal Ectopic Hyperparathyroidism |
| title_sort | rare case of hypercalcemia from mediastinal ectopic hyperparathyroidism |
| topic | primary hyperparathyroidism hypercalcemia ectopic disease endocrinology |
| url | https://www.mdpi.com/2308-3425/12/6/201 |
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