Effectiveness of Chatbot interventions for reducing caregiver burden: Protocol for a systematic review and meta-analysis

This protocol outlines a systematic review and meta-analysis examining the effectiveness of fully automated, AI-driven chatbot interventions in reducing subjective burden among informal caregivers. We will search 8 electronic databases (PubMed, Web of Science, Embase, CINAHL, MEDLINE, Cochrane Libra...

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Main Authors: Ravi Shankar, Anjali Bundele, Amartya Mukhopadhyay
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:MethodsX
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Online Access:http://www.sciencedirect.com/science/article/pii/S2215016125001189
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author Ravi Shankar
Anjali Bundele
Amartya Mukhopadhyay
author_facet Ravi Shankar
Anjali Bundele
Amartya Mukhopadhyay
author_sort Ravi Shankar
collection DOAJ
description This protocol outlines a systematic review and meta-analysis examining the effectiveness of fully automated, AI-driven chatbot interventions in reducing subjective burden among informal caregivers. We will search 8 electronic databases (PubMed, Web of Science, Embase, CINAHL, MEDLINE, Cochrane Library, PsycINFO, Scopus) and grey literature sources from January 2010 to December 2024 for randomized controlled trials (RCTs) meeting predefined eligibility criteria. The primary outcome is caregiver burden, assessed using validated scales such as the Zarit Burden Interview. Secondary outcomes encompass caregiver mental health, quality of life, self-efficacy and care recipient status. Two reviewers will independently perform study selection, data extraction, risk of bias evaluation using Cochrane RoB 2 tool, and appraise certainty of evidence utilizing the GRADE approach. We will conduct random-effects meta-analyses, subgroup analyses, and meta-regression to compute pooled effect estimates and explore heterogeneity. If quantitative synthesis is precluded, narrative synthesis will be undertaken following SWiM guideline. Caregiver partners will provide input on interpretation and dissemination of findings. • Protocol adheres to PRISMA-P reporting standards and will be prospectively registered in PROSPERO • Graphviz code for replicating the systematic review methodology diagram is provided • Review will yield critical evidence to guide development and implementation of chatbots into caregiver support services
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spelling doaj-art-e4e2b2c63a1c4a7fb9ad535e134ff9662025-08-20T03:32:03ZengElsevierMethodsX2215-01612025-06-011410327210.1016/j.mex.2025.103272Effectiveness of Chatbot interventions for reducing caregiver burden: Protocol for a systematic review and meta-analysisRavi Shankar0Anjali Bundele1Amartya Mukhopadhyay2Research and Innovation, Medical Affairs, Alexandra Hospital, Singapore, Singapore; Corresponding author at: Research and Innovation, Medical Affairs, Alexandra Hospital, Singapore, Singapore.Research and Innovation, Medical Affairs, Alexandra Hospital, Singapore, SingaporeDivision of Respiratory and Critical Care Medicine, Department of Medicine, National University Hospital, Singapore, SingaporeThis protocol outlines a systematic review and meta-analysis examining the effectiveness of fully automated, AI-driven chatbot interventions in reducing subjective burden among informal caregivers. We will search 8 electronic databases (PubMed, Web of Science, Embase, CINAHL, MEDLINE, Cochrane Library, PsycINFO, Scopus) and grey literature sources from January 2010 to December 2024 for randomized controlled trials (RCTs) meeting predefined eligibility criteria. The primary outcome is caregiver burden, assessed using validated scales such as the Zarit Burden Interview. Secondary outcomes encompass caregiver mental health, quality of life, self-efficacy and care recipient status. Two reviewers will independently perform study selection, data extraction, risk of bias evaluation using Cochrane RoB 2 tool, and appraise certainty of evidence utilizing the GRADE approach. We will conduct random-effects meta-analyses, subgroup analyses, and meta-regression to compute pooled effect estimates and explore heterogeneity. If quantitative synthesis is precluded, narrative synthesis will be undertaken following SWiM guideline. Caregiver partners will provide input on interpretation and dissemination of findings. • Protocol adheres to PRISMA-P reporting standards and will be prospectively registered in PROSPERO • Graphviz code for replicating the systematic review methodology diagram is provided • Review will yield critical evidence to guide development and implementation of chatbots into caregiver support serviceshttp://www.sciencedirect.com/science/article/pii/S2215016125001189Systematic Review and Meta-analysis.
spellingShingle Ravi Shankar
Anjali Bundele
Amartya Mukhopadhyay
Effectiveness of Chatbot interventions for reducing caregiver burden: Protocol for a systematic review and meta-analysis
MethodsX
Systematic Review and Meta-analysis.
title Effectiveness of Chatbot interventions for reducing caregiver burden: Protocol for a systematic review and meta-analysis
title_full Effectiveness of Chatbot interventions for reducing caregiver burden: Protocol for a systematic review and meta-analysis
title_fullStr Effectiveness of Chatbot interventions for reducing caregiver burden: Protocol for a systematic review and meta-analysis
title_full_unstemmed Effectiveness of Chatbot interventions for reducing caregiver burden: Protocol for a systematic review and meta-analysis
title_short Effectiveness of Chatbot interventions for reducing caregiver burden: Protocol for a systematic review and meta-analysis
title_sort effectiveness of chatbot interventions for reducing caregiver burden protocol for a systematic review and meta analysis
topic Systematic Review and Meta-analysis.
url http://www.sciencedirect.com/science/article/pii/S2215016125001189
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