Total Knee Arthroplasty in Ochronosis Arthropathy: A Case Report and Systematic Review

Introduction. Ochronosis arthropathy (OcA) is a rare condition which may be treated with total knee arthroplasty (TKA) at the end stage. The condition is often discovered only intraoperatively and the ideal choice of TKA is unknown. Case Presentation. A 54-year-old male with worsening chronic bilate...

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Main Authors: Wu Chean Lee, Tong Leng Tan, Ying Ho Chan
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Orthopedics
Online Access:http://dx.doi.org/10.1155/2019/1871856
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author Wu Chean Lee
Tong Leng Tan
Ying Ho Chan
author_facet Wu Chean Lee
Tong Leng Tan
Ying Ho Chan
author_sort Wu Chean Lee
collection DOAJ
description Introduction. Ochronosis arthropathy (OcA) is a rare condition which may be treated with total knee arthroplasty (TKA) at the end stage. The condition is often discovered only intraoperatively and the ideal choice of TKA is unknown. Case Presentation. A 54-year-old male with worsening chronic bilateral mechanical knee pain had failed conservative therapy. Posterior stabilised (PS), cemented TKA and patella resurfacing was performed. Intraoperatively, collagenous structures such as the menisci and cartilage were noted to be black. Histological examination showed deposition of large amorphous brown material suggestive of ochronosis. He recovered well and underwent TKA of the contralateral knee the following year. At 2 years postindex TKA, his outcome scores improved and he was satisfied. Discussion and Conclusion. With increasing TKA performed worldwide, a surgeon may eventually be surprised by the above findings once in their lifetime. However, OcA may be considered a likely diagnosis and it is safe to proceed with TKA. There is no particular TKA design that proved to be superior in our systematic review of 19 publications regarding TKA as all reported good outcomes. However, as the pathogenesis of OcA appears to be inflammatory in nature, we suggest using cemented PS TKA with resurfacing of the patella.
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spelling doaj-art-e4d2e4fcb77b422eb909834ea06c276a2025-02-03T01:12:28ZengWileyCase Reports in Orthopedics2090-67492090-67572019-01-01201910.1155/2019/18718561871856Total Knee Arthroplasty in Ochronosis Arthropathy: A Case Report and Systematic ReviewWu Chean Lee0Tong Leng Tan1Ying Ho Chan2Department of Orthopaedic Surgery, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, 308433, SingaporeDepartment of Orthopaedic Surgery, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, 308433, SingaporeDepartment of Orthopaedic Surgery, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, 308433, SingaporeIntroduction. Ochronosis arthropathy (OcA) is a rare condition which may be treated with total knee arthroplasty (TKA) at the end stage. The condition is often discovered only intraoperatively and the ideal choice of TKA is unknown. Case Presentation. A 54-year-old male with worsening chronic bilateral mechanical knee pain had failed conservative therapy. Posterior stabilised (PS), cemented TKA and patella resurfacing was performed. Intraoperatively, collagenous structures such as the menisci and cartilage were noted to be black. Histological examination showed deposition of large amorphous brown material suggestive of ochronosis. He recovered well and underwent TKA of the contralateral knee the following year. At 2 years postindex TKA, his outcome scores improved and he was satisfied. Discussion and Conclusion. With increasing TKA performed worldwide, a surgeon may eventually be surprised by the above findings once in their lifetime. However, OcA may be considered a likely diagnosis and it is safe to proceed with TKA. There is no particular TKA design that proved to be superior in our systematic review of 19 publications regarding TKA as all reported good outcomes. However, as the pathogenesis of OcA appears to be inflammatory in nature, we suggest using cemented PS TKA with resurfacing of the patella.http://dx.doi.org/10.1155/2019/1871856
spellingShingle Wu Chean Lee
Tong Leng Tan
Ying Ho Chan
Total Knee Arthroplasty in Ochronosis Arthropathy: A Case Report and Systematic Review
Case Reports in Orthopedics
title Total Knee Arthroplasty in Ochronosis Arthropathy: A Case Report and Systematic Review
title_full Total Knee Arthroplasty in Ochronosis Arthropathy: A Case Report and Systematic Review
title_fullStr Total Knee Arthroplasty in Ochronosis Arthropathy: A Case Report and Systematic Review
title_full_unstemmed Total Knee Arthroplasty in Ochronosis Arthropathy: A Case Report and Systematic Review
title_short Total Knee Arthroplasty in Ochronosis Arthropathy: A Case Report and Systematic Review
title_sort total knee arthroplasty in ochronosis arthropathy a case report and systematic review
url http://dx.doi.org/10.1155/2019/1871856
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AT tonglengtan totalkneearthroplastyinochronosisarthropathyacasereportandsystematicreview
AT yinghochan totalkneearthroplastyinochronosisarthropathyacasereportandsystematicreview