Gut microbiota-mediated pain sensitization: mechanisms and therapeutic implications

Emerging evidence has illuminated the pivotal role of gut microbiota in modulating pain sensitivity through bidirectional gut-brain interactions. Current research demonstrates that gut microbial communities significantly influence pain perception by regulating both central and peripheral sensitizati...

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Bibliographic Details
Main Authors: Minghe Zhao, Ling Zhang, Zhihui Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Pain Research
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fpain.2025.1626515/full
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