Association of Chronic Pancreatitis and Malignant Main Duct IPMN: A Rare but Difficult Clinical Problem

We report the case of a 70-year-old woman who consulted for recurrent short episodes of mild-to-moderate abdominal pain. Dilated main pancreatic duct was seen on CAT scan and magnetic resonance, with multiple calcifications and intraductal stones, typical in CP. However, for a more pronounced cystic...

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Main Authors: Zoltán Berger, Hernán De La Fuente, Manuel Meneses, Fernanda Matamala, Makarena Sepúlveda, Claudia Rojas
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Gastrointestinal Medicine
Online Access:http://dx.doi.org/10.1155/2017/8705195
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author Zoltán Berger
Hernán De La Fuente
Manuel Meneses
Fernanda Matamala
Makarena Sepúlveda
Claudia Rojas
author_facet Zoltán Berger
Hernán De La Fuente
Manuel Meneses
Fernanda Matamala
Makarena Sepúlveda
Claudia Rojas
author_sort Zoltán Berger
collection DOAJ
description We report the case of a 70-year-old woman who consulted for recurrent short episodes of mild-to-moderate abdominal pain. Dilated main pancreatic duct was seen on CAT scan and magnetic resonance, with multiple calcifications and intraductal stones, typical in CP. However, for a more pronounced cystic dilatation in the pancreatic head, we could not exclude the coexistence of a main duct IPMN. ERCP was performed, with pancreatic sphincterotomy and extraction of pancreatic stones, but, at the same time, mucin extrusion was seen from the dilated duct through the papilla. Pancreatoduodenectomy was performed. Surgery and histology confirmed malignant IPMN with the typical image of chronic pancreatitis and intraductal stones in the vicinity. The patient is doing well 4 years after the surgery, without recurrence of the malignant disease, with changes of chronic pancreatitis in the pancreatic remnant. This paper discusses the possible relationships between the two entities and emphasizes the need of differential diagnosis.
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institution Kabale University
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publishDate 2017-01-01
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series Case Reports in Gastrointestinal Medicine
spelling doaj-art-e4cbfc001bfc4f0a9e2fb0ce0426e7f22025-02-03T01:21:21ZengWileyCase Reports in Gastrointestinal Medicine2090-65282090-65362017-01-01201710.1155/2017/87051958705195Association of Chronic Pancreatitis and Malignant Main Duct IPMN: A Rare but Difficult Clinical ProblemZoltán Berger0Hernán De La Fuente1Manuel Meneses2Fernanda Matamala3Makarena Sepúlveda4Claudia Rojas5Departamento Medicina, Sección Gastroenterología, Hospital Clínico Universidad de Chile, Santiago, ChileClínica Santa María, Santiago, ChileFundación Arturo López Pérez, Santiago, ChileUniversidad Andres Bello, Santiago, ChileUniversidad de los Andes, Santiago, ChileUniversidad de los Andes, Santiago, ChileWe report the case of a 70-year-old woman who consulted for recurrent short episodes of mild-to-moderate abdominal pain. Dilated main pancreatic duct was seen on CAT scan and magnetic resonance, with multiple calcifications and intraductal stones, typical in CP. However, for a more pronounced cystic dilatation in the pancreatic head, we could not exclude the coexistence of a main duct IPMN. ERCP was performed, with pancreatic sphincterotomy and extraction of pancreatic stones, but, at the same time, mucin extrusion was seen from the dilated duct through the papilla. Pancreatoduodenectomy was performed. Surgery and histology confirmed malignant IPMN with the typical image of chronic pancreatitis and intraductal stones in the vicinity. The patient is doing well 4 years after the surgery, without recurrence of the malignant disease, with changes of chronic pancreatitis in the pancreatic remnant. This paper discusses the possible relationships between the two entities and emphasizes the need of differential diagnosis.http://dx.doi.org/10.1155/2017/8705195
spellingShingle Zoltán Berger
Hernán De La Fuente
Manuel Meneses
Fernanda Matamala
Makarena Sepúlveda
Claudia Rojas
Association of Chronic Pancreatitis and Malignant Main Duct IPMN: A Rare but Difficult Clinical Problem
Case Reports in Gastrointestinal Medicine
title Association of Chronic Pancreatitis and Malignant Main Duct IPMN: A Rare but Difficult Clinical Problem
title_full Association of Chronic Pancreatitis and Malignant Main Duct IPMN: A Rare but Difficult Clinical Problem
title_fullStr Association of Chronic Pancreatitis and Malignant Main Duct IPMN: A Rare but Difficult Clinical Problem
title_full_unstemmed Association of Chronic Pancreatitis and Malignant Main Duct IPMN: A Rare but Difficult Clinical Problem
title_short Association of Chronic Pancreatitis and Malignant Main Duct IPMN: A Rare but Difficult Clinical Problem
title_sort association of chronic pancreatitis and malignant main duct ipmn a rare but difficult clinical problem
url http://dx.doi.org/10.1155/2017/8705195
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