THE INTRACELLULAR AND CIRCULATING POOLS OF PROTEASOMES: THE VALUE AT CANCER IN DIFFERENT LOCATIONS
This review presents the structure of the proteasome system, discusses its involvement in the pathogenesis of many cancers, including the process of metastasis. It describes the distinctive structural characteristics of intra- and extracellular pools of proteasomes, possible ways of their exit into...
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| Format: | Article |
| Language: | Russian |
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Russian Academy of Sciences, Tomsk National Research Medical Center
2016-02-01
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| Series: | Сибирский онкологический журнал |
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| Online Access: | https://www.siboncoj.ru/jour/article/view/206 |
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| author | E. E. Shashova E. S. Kolegova I. V. Kondakova A. A. Zavyalov |
| author_facet | E. E. Shashova E. S. Kolegova I. V. Kondakova A. A. Zavyalov |
| author_sort | E. E. Shashova |
| collection | DOAJ |
| description | This review presents the structure of the proteasome system, discusses its involvement in the pathogenesis of many cancers, including the process of metastasis. It describes the distinctive structural characteristics of intra- and extracellular pools of proteasomes, possible ways of their exit into the extracellular space and their forms of existence outside the cell. Also in the present review discusses the importance of circulating proteasomes for prognosis course of the cancer. |
| format | Article |
| id | doaj-art-e4c8cf6dbb654e2dbbdeb15a22b2417e |
| institution | DOAJ |
| issn | 1814-4861 2312-3168 |
| language | Russian |
| publishDate | 2016-02-01 |
| publisher | Russian Academy of Sciences, Tomsk National Research Medical Center |
| record_format | Article |
| series | Сибирский онкологический журнал |
| spelling | doaj-art-e4c8cf6dbb654e2dbbdeb15a22b2417e2025-08-20T02:59:11ZrusRussian Academy of Sciences, Tomsk National Research Medical CenterСибирский онкологический журнал1814-48612312-31682016-02-01067682206THE INTRACELLULAR AND CIRCULATING POOLS OF PROTEASOMES: THE VALUE AT CANCER IN DIFFERENT LOCATIONSE. E. Shashova0E. S. Kolegova1I. V. Kondakova2A. A. Zavyalov3Tomsk Cancer Research InstituteTomsk Cancer Research Institute; Siberian State Medical University, TomskTomsk Cancer Research InstituteTomsk Cancer Research Institute; Siberian State Medical University, TomskThis review presents the structure of the proteasome system, discusses its involvement in the pathogenesis of many cancers, including the process of metastasis. It describes the distinctive structural characteristics of intra- and extracellular pools of proteasomes, possible ways of their exit into the extracellular space and their forms of existence outside the cell. Also in the present review discusses the importance of circulating proteasomes for prognosis course of the cancer.https://www.siboncoj.ru/jour/article/view/206proteasome system, the extracellular forms of the proteasomes, cancer, metastasis |
| spellingShingle | E. E. Shashova E. S. Kolegova I. V. Kondakova A. A. Zavyalov THE INTRACELLULAR AND CIRCULATING POOLS OF PROTEASOMES: THE VALUE AT CANCER IN DIFFERENT LOCATIONS Сибирский онкологический журнал proteasome system, the extracellular forms of the proteasomes, cancer, metastasis |
| title | THE INTRACELLULAR AND CIRCULATING POOLS OF PROTEASOMES: THE VALUE AT CANCER IN DIFFERENT LOCATIONS |
| title_full | THE INTRACELLULAR AND CIRCULATING POOLS OF PROTEASOMES: THE VALUE AT CANCER IN DIFFERENT LOCATIONS |
| title_fullStr | THE INTRACELLULAR AND CIRCULATING POOLS OF PROTEASOMES: THE VALUE AT CANCER IN DIFFERENT LOCATIONS |
| title_full_unstemmed | THE INTRACELLULAR AND CIRCULATING POOLS OF PROTEASOMES: THE VALUE AT CANCER IN DIFFERENT LOCATIONS |
| title_short | THE INTRACELLULAR AND CIRCULATING POOLS OF PROTEASOMES: THE VALUE AT CANCER IN DIFFERENT LOCATIONS |
| title_sort | intracellular and circulating pools of proteasomes the value at cancer in different locations |
| topic | proteasome system, the extracellular forms of the proteasomes, cancer, metastasis |
| url | https://www.siboncoj.ru/jour/article/view/206 |
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