Insightful chemistry of molecular docking studies and ADMET profiling of 4-amino-1,2,4-triazole scaffolds as potential inhibitor of DprE1 enzymes as antitubercular agents
Abstract Background Airborne transmission of the bacterial illness tuberculosis (TB) is attributed to Mycobacterium tuberculosis (Mtb). Mycobacterium tuberculosis, a multidrug-resistant strain, spreads quickly and is the cause of multidrug-resistant tuberculosis (MDRTB). A study was conducted to inv...
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| Main Authors: | Santosh Prasad Chaudhary Kurmi, Dipanjan Karati |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer
2025-06-01
|
| Series: | Discover Chemistry |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s44371-025-00208-w |
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