Antibacterial Action of <i>Lippia origanoides</i> Essential Oil

Bacterial resistance to antibiotics makes infections increasingly difficult to fight. In this context, the antimicrobial capacity of <i>Lippia origanoides</i> proved to be a relevant alternative. The purpose of this review is to evaluate the antibacterial activity of this essential oil a...

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Main Authors: Francisco Sérgio da Silva Sousa, Dicla Aline Semedo da Veiga, Bernardina De Paixão Santos, Rafaelle Cavalcanti de Lira, Sávio Benvindo Ferreira
Format: Article
Language:English
Published: MDPI AG 2024-04-01
Series:Proceedings
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Online Access:https://www.mdpi.com/2504-3900/103/1/77
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Summary:Bacterial resistance to antibiotics makes infections increasingly difficult to fight. In this context, the antimicrobial capacity of <i>Lippia origanoides</i> proved to be a relevant alternative. The purpose of this review is to evaluate the antibacterial activity of this essential oil against bacterial strains. This is a narrative review of the literature using the following guiding question: “Does <i>Lippia origanoides</i> essential oil have antimicrobial activity against bacterial strains?”. The descriptors “<i>Lippia origanoides</i>” and “Antimicrobial activity” were applied to the PubMed, Virtual Health Library (VHL) and Embase databases. The inclusion criteria were as follows: contain, whether in the title, abstract or body of the text, a relationship with the antibacterial activity of <i>L. origanoides</i>, and the possibility of accessing the full article. A total of 62 articles were found and 19 studies were chosen. A total of 13 bacteria were analyzed in the tests and the Minimum Inhibitory Concentration (MIC) was as follows: <i>Bacillus cereus</i> (0.62 μL/mL), <i>Bacillus subtilis</i> (1.25 μL/mL), <i>Staphylococcus aureus</i> (1.25–60 μL/mL), <i>Chromobacterium violaceum</i> (0.37 μL/mL), <i>Escherichia coli</i> (0.15–60 μL/mL), <i>Pseudomonas aeruginosa</i> (240 μL/mL), <i>Salmonella cholerasuis</i> (30 μL/mL), <i>Salmonella thypimurium</i> (1.25 μL/mL) and <i>Vibrio parahaemolyticus</i> (0.313 μL/mL). In <i>Bifidobacterium</i> breve and <i>Lactobacillus acidophilus</i>, the Minimum Bactericidal Concentration (MBC) was, respectively, 50 μL/mL and 3.135 μL/mL. In <i>Staphylococcus epidermidis</i> and <i>Salmonella enteritidis</i>, there was only MIC<sub>50</sub> (concentration to inhibit 50% of the sample), specifically, 0.37–3.0 μL/mL and 0.37 μL/mL. In total, 27.3% of articles evaluated the antibiofilm capacity of <i>L. origanoides</i>, and the inhibition of biofilm formation reached more than 70% in <i>E. coli</i> and <i>S. aureus</i>. <i>Lippia origanoides</i> essential oil revealed antimicrobial activity in all studies. Ultimately, <i>P. aeruginosa</i> proved to be a strain that still requires further experimentation.
ISSN:2504-3900