The Role of Trifluoromethyl and Trifluoromethoxy Groups in Medicinal Chemistry: Implications for Drug Design
One of the key strategies in drug design involves modifying molecular scaffolds with specific chemical groups, or side chains, to enhance biological and physicochemical properties. These modifications can strengthen interactions with biological targets or improve pharmacokinetic and physicochemical...
Saved in:
| Main Authors: | Manuel Novás, Maria J. Matos |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-07-01
|
| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/30/14/3009 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Synthesis of Ethynyl Trifluoromethyl Sulfide and Its Application to the Synthesis of CF<sub>3</sub>S-Containing Triazoles
by: Alejandra Riesco-Domínguez, et al.
Published: (2025-05-01) -
Bioactivity of Synthesized Trifluoromethyl Thioxanthone Analogues
by: Murad Abualhasan, et al.
Published: (2025-04-01) -
Advances in photocatalytic research on decarboxylative trifluoromethylation of trifluoroacetic acid and derivatives
by: Fang-Fang Tan, et al.
Published: (2025-05-01) -
Crystal structure of 1-[(4-chlorophenyl)diphenylylmethyl]-3-(trifluoromethyl)-1H-pyrazole
by: Firudin I. Guseinov, et al.
Published: (2025-03-01) -
1,2-Oxidative Trifluoromethylation of Olefin with Ag(O<sub>2</sub>CCF<sub>2</sub>SO<sub>2</sub>F) and O<sub>2</sub>: Synthesis of α-Trifluoromethyl Ketones
by: Shengxue Zhang, et al.
Published: (2024-11-01)