Vascularized in vitro bone model as 3D quadruple culture with primary human osteoblasts, osteocytes, osteoclasts and endothelial cells

With an aging population worldwide, research into bone metabolism and novel therapies for damaged and diseased bone is essential. Bone is a vascularized, dynamic tissue that undergoes a constant remodeling process mediated by osteocytes, osteoblasts and osteoclasts. In this study, a complex 3D in vi...

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Bibliographic Details
Main Authors: Katharina Wirsig, Nina Bürger, Lisa Fleischhauer, Nele Louisa Preuß, Anne Bernhardt
Format: Article
Language:English
Published: Elsevier 2025-10-01
Series:Materials Today Bio
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Online Access:http://www.sciencedirect.com/science/article/pii/S2590006425007240
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