Simultaneous determination of 74 pesticide residues in Panax notoginseng by QuEChERS coupled with gas chromatography tandem mass spectrometry
This study established a method for the simultaneous determination of 74 pesticide residues in Panax notoginseng by QuEChERS pretreatment method coupled with GC-MS/MS, and carried out pesticide residue analysis on 20 batches of market samples in China. The samples were extracted with acetonitrile, c...
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| Format: | Article |
| Language: | English |
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Tsinghua University Press
2021-03-01
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| Series: | Food Science and Human Wellness |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213453021000227 |
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| author | Huijun Li Jieshan Wu Chao Chen Wenfeng Xin Wensheng Zhang |
| author_facet | Huijun Li Jieshan Wu Chao Chen Wenfeng Xin Wensheng Zhang |
| author_sort | Huijun Li |
| collection | DOAJ |
| description | This study established a method for the simultaneous determination of 74 pesticide residues in Panax notoginseng by QuEChERS pretreatment method coupled with GC-MS/MS, and carried out pesticide residue analysis on 20 batches of market samples in China. The samples were extracted with acetonitrile, cleaned up with primary secondary amine (PSA) and octadecylsilane (C18) and determined by GC-MS/MS in multiple reaction monitoring (MRM) mode. Matrix-matched calibration was recommended to combat the matrix effect. A good linearity was observed in the range of 10 − 500 ng/mL with correlation coefficients ≥ 0.9950. The mean recoveries for most of the pesticides were in the range of 70% − 120% with RSD < 20%. The limits of detection ranged 0.28–2.00 μg/kg, while the limits of quantification were 0.94–6.65 μg/kg. Following the application of “top-down” approach, the expanded measurement uncertainty for all the analytes was <30%. The proposed method was successfully applied to determine pesticide residues in 20 market samples in China, where 9 pesticides were detected and quintozene exceeded the criteria domestically and abroad. |
| format | Article |
| id | doaj-art-e46f552df1f745a0aba3515e33a64f5f |
| institution | Kabale University |
| issn | 2213-4530 |
| language | English |
| publishDate | 2021-03-01 |
| publisher | Tsinghua University Press |
| record_format | Article |
| series | Food Science and Human Wellness |
| spelling | doaj-art-e46f552df1f745a0aba3515e33a64f5f2025-02-03T11:08:27ZengTsinghua University PressFood Science and Human Wellness2213-45302021-03-01102241250Simultaneous determination of 74 pesticide residues in Panax notoginseng by QuEChERS coupled with gas chromatography tandem mass spectrometryHuijun Li0Jieshan Wu1Chao Chen2Wenfeng Xin3Wensheng Zhang4Engineering Research Center of Natural Medicine, Ministry of Education, Beijing Normal University at Zhuhai 519087, China; Zhuhai Branch of State Key Laboratory of Earth Surface Processes and Resource Ecology, Beijing Normal University at Zhuhai 519087, China; Beijing Key Laboratory of Traditional Chinese Medicine Protection and Utilization, Faculty of Geographical Science, Beijing Normal University, Beijing 100875, ChinaGongbei customs of the People's Republic of China, Zhuhai 519000, ChinaEngineering Research Center of Natural Medicine, Ministry of Education, Beijing Normal University at Zhuhai 519087, China; Zhuhai Branch of State Key Laboratory of Earth Surface Processes and Resource Ecology, Beijing Normal University at Zhuhai 519087, China; Beijing Key Laboratory of Traditional Chinese Medicine Protection and Utilization, Faculty of Geographical Science, Beijing Normal University, Beijing 100875, ChinaNational and Local United Engineering Research Center for Panax Notoginseng Resources Protection and Utilization Technology, Kunming 650000, ChinaEngineering Research Center of Natural Medicine, Ministry of Education, Beijing Normal University at Zhuhai 519087, China; Zhuhai Branch of State Key Laboratory of Earth Surface Processes and Resource Ecology, Beijing Normal University at Zhuhai 519087, China; Beijing Key Laboratory of Traditional Chinese Medicine Protection and Utilization, Faculty of Geographical Science, Beijing Normal University, Beijing 100875, China; Corresponding author. Beijing Normal University, Beijing 100875, China.This study established a method for the simultaneous determination of 74 pesticide residues in Panax notoginseng by QuEChERS pretreatment method coupled with GC-MS/MS, and carried out pesticide residue analysis on 20 batches of market samples in China. The samples were extracted with acetonitrile, cleaned up with primary secondary amine (PSA) and octadecylsilane (C18) and determined by GC-MS/MS in multiple reaction monitoring (MRM) mode. Matrix-matched calibration was recommended to combat the matrix effect. A good linearity was observed in the range of 10 − 500 ng/mL with correlation coefficients ≥ 0.9950. The mean recoveries for most of the pesticides were in the range of 70% − 120% with RSD < 20%. The limits of detection ranged 0.28–2.00 μg/kg, while the limits of quantification were 0.94–6.65 μg/kg. Following the application of “top-down” approach, the expanded measurement uncertainty for all the analytes was <30%. The proposed method was successfully applied to determine pesticide residues in 20 market samples in China, where 9 pesticides were detected and quintozene exceeded the criteria domestically and abroad.http://www.sciencedirect.com/science/article/pii/S2213453021000227Panax notoginsengQuEChERSGC-MS/MSPesticide residues |
| spellingShingle | Huijun Li Jieshan Wu Chao Chen Wenfeng Xin Wensheng Zhang Simultaneous determination of 74 pesticide residues in Panax notoginseng by QuEChERS coupled with gas chromatography tandem mass spectrometry Food Science and Human Wellness Panax notoginseng QuEChERS GC-MS/MS Pesticide residues |
| title | Simultaneous determination of 74 pesticide residues in Panax notoginseng by QuEChERS coupled with gas chromatography tandem mass spectrometry |
| title_full | Simultaneous determination of 74 pesticide residues in Panax notoginseng by QuEChERS coupled with gas chromatography tandem mass spectrometry |
| title_fullStr | Simultaneous determination of 74 pesticide residues in Panax notoginseng by QuEChERS coupled with gas chromatography tandem mass spectrometry |
| title_full_unstemmed | Simultaneous determination of 74 pesticide residues in Panax notoginseng by QuEChERS coupled with gas chromatography tandem mass spectrometry |
| title_short | Simultaneous determination of 74 pesticide residues in Panax notoginseng by QuEChERS coupled with gas chromatography tandem mass spectrometry |
| title_sort | simultaneous determination of 74 pesticide residues in panax notoginseng by quechers coupled with gas chromatography tandem mass spectrometry |
| topic | Panax notoginseng QuEChERS GC-MS/MS Pesticide residues |
| url | http://www.sciencedirect.com/science/article/pii/S2213453021000227 |
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