De Quervain’s Tenosynovitis Virally Exacerbated by SARS-CoV-2 and Influenza Infections: A Case Report

We present the case of a fully vaccinated 39-year-old male with no pertinent past medical history who initially presented with De Quervain’s tenosynovitis which was successfully treated with a corticosteroid injection. His symptoms recurred during a COVID-19 infection, which was treated with a repea...

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Bibliographic Details
Main Authors: Maria Gergoudis, Logan Laubach, Glenn E. Lee, Jeffrey R. Donowitz
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Case Reports in Infectious Diseases
Online Access:http://dx.doi.org/10.1155/crdi/5117572
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Summary:We present the case of a fully vaccinated 39-year-old male with no pertinent past medical history who initially presented with De Quervain’s tenosynovitis which was successfully treated with a corticosteroid injection. His symptoms recurred during a COVID-19 infection, which was treated with a repeat corticosteroid injection. Symptoms recurred during an influenza infection and were subsequently treated with a first dorsal compartment release. The etiology of De Quervain’s tenosynovitis remains unclear. It has classically been categorized as a noninflammatory degenerative process, but recent evidence suggests a possible inflammatory connection. Here, we present a case of recurrent De Quervain’s tenosynovitis exacerbated by two distinct viral infections. We hypothesize that viral-induced systemic inflammation led to localized recurrence of inflammation within the tendon sheath. Further studies including cytokine analysis and inflammatory markers are needed to advance this hypothesis.
ISSN:2090-6633