The BRD4 Inhibitor dBET57 Exerts Anticancer Effects by Targeting Superenhancer-Related Genes in Neuroblastoma

The BRD4 Inhibitor dBET57 Exerts Anticancer Effects by Targeting Superenhancer-Related Genes in Neuroblastoma

Neuroblastoma (NB) is the most common solid tumor of the neural crest cell origin in children and has a poor prognosis in high-risk patients. The oncogene MYCN was found to be amplified at extremely high levels in approximately 20% of neuroblastoma cases. In recent years, research on the targeted hy...

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Main Authors: Si-Qi Jia, Ran Zhuo, Zi-Mu Zhang, Yang Yang, Yan-Fang Tao, Jian-Wei Wang, Xiao-Lu Li, Yi Xie, Gen Li, Di Wu, Yan-Ling Chen, Juan-Juan Yu, Chen-xi Feng, Zhi-Heng Li, Rong-Fang Zhou, Ran-Dong Yang, Peng-Cheng Yang, Bi Zhou, Xiao-Mei Wan, Yu-Meng Wu, Wan-Yan Jiao, Ni-Na Zhou, Fang Fang, Jian Pan
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2022/7945884
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