GLIM criteria for definition of malnutrition in peritoneal dialysis: a new aspect of nutritional assessment
Background The aim of our study was to evaluate the effectiveness of Global Leadership Initiative on Malnutrition (GLIM) criteria in assessing malnutrition within the peritoneal dialysis (PD) population.Methods We conducted a retrospective analysis involving 1057 PD patients across multiple institut...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2024-12-01
|
| Series: | Renal Failure |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/0886022X.2024.2337290 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832591133553721344 |
|---|---|
| author | Dao Wang Jun Yin Wen Liao Xiaoran Feng Fengping Zhang |
| author_facet | Dao Wang Jun Yin Wen Liao Xiaoran Feng Fengping Zhang |
| author_sort | Dao Wang |
| collection | DOAJ |
| description | Background The aim of our study was to evaluate the effectiveness of Global Leadership Initiative on Malnutrition (GLIM) criteria in assessing malnutrition within the peritoneal dialysis (PD) population.Methods We conducted a retrospective analysis involving 1057 PD patients across multiple institutions, characterized by an age of 56.1 ± 14.4 years, 464 (43.9%) female, and a median follow-up of 45 (25, 68) months. Malnutrition was diagnosed according to GLIM criteria. The endpoint event was overall mortality. The survival rate and hazard ratio (HR) of death between malnutrition and well-nourished were analyzed in all patients and various subgroups. Receiver operator characteristic curve and integrated discrimination improvement (IDI) were used to distinguish the efficacy of the nutritional tools prediction model.Results According to the GLIM criteria, the prevalence of malnutrition among the study population was 34.9%. The adjusted HR of overall mortality was 2.91 (2.39 − 3.54, p < 0.001) for malnutrition versus well-nourished. In sensitivity analyses, the HR remained robust except the cardiovascular disease subgroup. The area under the curve of GLIM predicting 5-year mortality was 0.65 (0.62–0.68, p < 0.001). As a complex model for forecast the long-term mortality, the performance of adjusted factors combined with GLIM was poorer than combined malnutrition inflammation score (MIS) (IDI >0, p < 0.001), but fitter than combined geriatric nutritional risk index (GNRI) (IDI <0, p < 0.001).Conclusions The GLIM criteria provide a viable tool for nutritional assessment in patients with PD, and malnutrition defined according to the GLIM can predict prognosis with an acceptable performance. |
| format | Article |
| id | doaj-art-e42855137f7e4579a2bba349468e4c21 |
| institution | Kabale University |
| issn | 0886-022X 1525-6049 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Renal Failure |
| spelling | doaj-art-e42855137f7e4579a2bba349468e4c212025-01-23T04:17:49ZengTaylor & Francis GroupRenal Failure0886-022X1525-60492024-12-0146110.1080/0886022X.2024.2337290GLIM criteria for definition of malnutrition in peritoneal dialysis: a new aspect of nutritional assessmentDao Wang0Jun Yin1Wen Liao2Xiaoran Feng3Fengping Zhang4Department of Nephrology, Pingxiang People’s Hospital, Pingxiang, ChinaDepartment of Nephrology, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Nephrology, Pingxiang People’s Hospital, Pingxiang, ChinaDepartment of Nephrology, Jiujiang First People’s Hospital, Jiujiang, ChinaDepartment of Nephrology, Jiujiang First People’s Hospital, Jiujiang, ChinaBackground The aim of our study was to evaluate the effectiveness of Global Leadership Initiative on Malnutrition (GLIM) criteria in assessing malnutrition within the peritoneal dialysis (PD) population.Methods We conducted a retrospective analysis involving 1057 PD patients across multiple institutions, characterized by an age of 56.1 ± 14.4 years, 464 (43.9%) female, and a median follow-up of 45 (25, 68) months. Malnutrition was diagnosed according to GLIM criteria. The endpoint event was overall mortality. The survival rate and hazard ratio (HR) of death between malnutrition and well-nourished were analyzed in all patients and various subgroups. Receiver operator characteristic curve and integrated discrimination improvement (IDI) were used to distinguish the efficacy of the nutritional tools prediction model.Results According to the GLIM criteria, the prevalence of malnutrition among the study population was 34.9%. The adjusted HR of overall mortality was 2.91 (2.39 − 3.54, p < 0.001) for malnutrition versus well-nourished. In sensitivity analyses, the HR remained robust except the cardiovascular disease subgroup. The area under the curve of GLIM predicting 5-year mortality was 0.65 (0.62–0.68, p < 0.001). As a complex model for forecast the long-term mortality, the performance of adjusted factors combined with GLIM was poorer than combined malnutrition inflammation score (MIS) (IDI >0, p < 0.001), but fitter than combined geriatric nutritional risk index (GNRI) (IDI <0, p < 0.001).Conclusions The GLIM criteria provide a viable tool for nutritional assessment in patients with PD, and malnutrition defined according to the GLIM can predict prognosis with an acceptable performance.https://www.tandfonline.com/doi/10.1080/0886022X.2024.2337290GLIMmalnutritionassessmentperitoneal dialysisprognosis |
| spellingShingle | Dao Wang Jun Yin Wen Liao Xiaoran Feng Fengping Zhang GLIM criteria for definition of malnutrition in peritoneal dialysis: a new aspect of nutritional assessment Renal Failure GLIM malnutrition assessment peritoneal dialysis prognosis |
| title | GLIM criteria for definition of malnutrition in peritoneal dialysis: a new aspect of nutritional assessment |
| title_full | GLIM criteria for definition of malnutrition in peritoneal dialysis: a new aspect of nutritional assessment |
| title_fullStr | GLIM criteria for definition of malnutrition in peritoneal dialysis: a new aspect of nutritional assessment |
| title_full_unstemmed | GLIM criteria for definition of malnutrition in peritoneal dialysis: a new aspect of nutritional assessment |
| title_short | GLIM criteria for definition of malnutrition in peritoneal dialysis: a new aspect of nutritional assessment |
| title_sort | glim criteria for definition of malnutrition in peritoneal dialysis a new aspect of nutritional assessment |
| topic | GLIM malnutrition assessment peritoneal dialysis prognosis |
| url | https://www.tandfonline.com/doi/10.1080/0886022X.2024.2337290 |
| work_keys_str_mv | AT daowang glimcriteriafordefinitionofmalnutritioninperitonealdialysisanewaspectofnutritionalassessment AT junyin glimcriteriafordefinitionofmalnutritioninperitonealdialysisanewaspectofnutritionalassessment AT wenliao glimcriteriafordefinitionofmalnutritioninperitonealdialysisanewaspectofnutritionalassessment AT xiaoranfeng glimcriteriafordefinitionofmalnutritioninperitonealdialysisanewaspectofnutritionalassessment AT fengpingzhang glimcriteriafordefinitionofmalnutritioninperitonealdialysisanewaspectofnutritionalassessment |