Investigating size-dependent selectivity in benzaldehyde reductive amination via Ni nanoparticles

Selectivity control is a fundamental focus in catalysis chemistry, as it directly reflects the efficiency and efficacy of catalytic processes. While catalysis often involves intricate and cascade reaction steps using nanoparticle (NP) catalysts, the mechanism behind the size effect of nanoparticles...

Full description

Saved in:
Bibliographic Details
Main Authors: Yunong Li, Ching Kit Tommy Wun, Tianxiang Chen, Tsz Woon Benedict Lo
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Materials Today Catalysis
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2949754X25000134
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850218977178943488
author Yunong Li
Ching Kit Tommy Wun
Tianxiang Chen
Tsz Woon Benedict Lo
author_facet Yunong Li
Ching Kit Tommy Wun
Tianxiang Chen
Tsz Woon Benedict Lo
author_sort Yunong Li
collection DOAJ
description Selectivity control is a fundamental focus in catalysis chemistry, as it directly reflects the efficiency and efficacy of catalytic processes. While catalysis often involves intricate and cascade reaction steps using nanoparticle (NP) catalysts, the mechanism behind the size effect of nanoparticles on product selectivity has not been fully explored. We herein prepared a series of Ni-containing zeolitic catalysts in which the Ni NPs are uniformly supported on the mesopores and outer surfaces of H-ZSM-5 zeolites. The dynamic formation of Ni NPs from highly dispersed Ni precursors was monitored using transmission electron microscopy, in-situ X-ray pair distribution function, and in-situ X-ray absorption fine structure analysis. The metal nanoparticle size was carefully controlled between 3.72(5) nm and 11.91(7) by controlling the reduction temperature. We evaluated the catalytic performance of Ni NPs using the reductive amination of benzaldehyde in batch reactors at low temperatures. This reaction inherently favors the formation of a series of products, suffering highly from selectivity issues. Our results revealed a size-dependent behavior in reaction efficiency, with the catalyst achieving the highest catalytic activity (93 % selectivity in primary amine) at a particle size of 5.62(3) nm. This optimal performance is attributed to a balanced interplay between hydrogenation and amination capabilities. These findings highlight the intricate relationship between nanoparticle size and catalytic performance, emphasizing the necessity for precise optimization in catalyst design to enhance selectivity and sustainability in industrial applications.
format Article
id doaj-art-e41f8bcedf46453c8bf9e3049bdf2bdb
institution OA Journals
issn 2949-754X
language English
publishDate 2025-06-01
publisher Elsevier
record_format Article
series Materials Today Catalysis
spelling doaj-art-e41f8bcedf46453c8bf9e3049bdf2bdb2025-08-20T02:07:31ZengElsevierMaterials Today Catalysis2949-754X2025-06-01910010010.1016/j.mtcata.2025.100100Investigating size-dependent selectivity in benzaldehyde reductive amination via Ni nanoparticlesYunong Li0Ching Kit Tommy Wun1Tianxiang Chen2Tsz Woon Benedict Lo3State Key Laboratory of Chemical Biology and Drug Discovery, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Hong Kong SAR; The Hong Kong Polytechnic University Shenzhen Research Institute, The Hong Kong Polytechnic University, Shenzhen 518057, ChinaState Key Laboratory of Chemical Biology and Drug Discovery, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Hong Kong SAR; The Hong Kong Polytechnic University Shenzhen Research Institute, The Hong Kong Polytechnic University, Shenzhen 518057, ChinaState Key Laboratory of Chemical Biology and Drug Discovery, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Hong Kong SAR; The Hong Kong Polytechnic University Shenzhen Research Institute, The Hong Kong Polytechnic University, Shenzhen 518057, China; Corresponding authors at: State Key Laboratory of Chemical Biology and Drug Discovery, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Hong Kong SAR.State Key Laboratory of Chemical Biology and Drug Discovery, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Hong Kong SAR; The Hong Kong Polytechnic University Shenzhen Research Institute, The Hong Kong Polytechnic University, Shenzhen 518057, China; Department of Applied Physics, The Hong Kong Polytechnic University, Hung Hom, Hong Kong SAR; Corresponding authors at: State Key Laboratory of Chemical Biology and Drug Discovery, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Hong Kong SAR.Selectivity control is a fundamental focus in catalysis chemistry, as it directly reflects the efficiency and efficacy of catalytic processes. While catalysis often involves intricate and cascade reaction steps using nanoparticle (NP) catalysts, the mechanism behind the size effect of nanoparticles on product selectivity has not been fully explored. We herein prepared a series of Ni-containing zeolitic catalysts in which the Ni NPs are uniformly supported on the mesopores and outer surfaces of H-ZSM-5 zeolites. The dynamic formation of Ni NPs from highly dispersed Ni precursors was monitored using transmission electron microscopy, in-situ X-ray pair distribution function, and in-situ X-ray absorption fine structure analysis. The metal nanoparticle size was carefully controlled between 3.72(5) nm and 11.91(7) by controlling the reduction temperature. We evaluated the catalytic performance of Ni NPs using the reductive amination of benzaldehyde in batch reactors at low temperatures. This reaction inherently favors the formation of a series of products, suffering highly from selectivity issues. Our results revealed a size-dependent behavior in reaction efficiency, with the catalyst achieving the highest catalytic activity (93 % selectivity in primary amine) at a particle size of 5.62(3) nm. This optimal performance is attributed to a balanced interplay between hydrogenation and amination capabilities. These findings highlight the intricate relationship between nanoparticle size and catalytic performance, emphasizing the necessity for precise optimization in catalyst design to enhance selectivity and sustainability in industrial applications.http://www.sciencedirect.com/science/article/pii/S2949754X25000134Ni nanoparticleSize effectReductive amination reactionPrecise controlIn-situ characterizationCatalyst design
spellingShingle Yunong Li
Ching Kit Tommy Wun
Tianxiang Chen
Tsz Woon Benedict Lo
Investigating size-dependent selectivity in benzaldehyde reductive amination via Ni nanoparticles
Materials Today Catalysis
Ni nanoparticle
Size effect
Reductive amination reaction
Precise control
In-situ characterization
Catalyst design
title Investigating size-dependent selectivity in benzaldehyde reductive amination via Ni nanoparticles
title_full Investigating size-dependent selectivity in benzaldehyde reductive amination via Ni nanoparticles
title_fullStr Investigating size-dependent selectivity in benzaldehyde reductive amination via Ni nanoparticles
title_full_unstemmed Investigating size-dependent selectivity in benzaldehyde reductive amination via Ni nanoparticles
title_short Investigating size-dependent selectivity in benzaldehyde reductive amination via Ni nanoparticles
title_sort investigating size dependent selectivity in benzaldehyde reductive amination via ni nanoparticles
topic Ni nanoparticle
Size effect
Reductive amination reaction
Precise control
In-situ characterization
Catalyst design
url http://www.sciencedirect.com/science/article/pii/S2949754X25000134
work_keys_str_mv AT yunongli investigatingsizedependentselectivityinbenzaldehydereductiveaminationvianinanoparticles
AT chingkittommywun investigatingsizedependentselectivityinbenzaldehydereductiveaminationvianinanoparticles
AT tianxiangchen investigatingsizedependentselectivityinbenzaldehydereductiveaminationvianinanoparticles
AT tszwoonbenedictlo investigatingsizedependentselectivityinbenzaldehydereductiveaminationvianinanoparticles