Pigment epithelium detachment with thickened choroid in a preterm infant at term-equivalent age: a case report
Pigment epithelial detachment (PED) is well-documented in adult retinal diseases but is rarely reported in neonates. This case describes a preterm infant, born at 31 weeks, who developed PED with thickened choroid at term-equivalent age, detected using handheld OCT. The PED emerged at 39 weeks postm...
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Frontiers Media S.A.
2025-08-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2025.1581191/full |
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| author | Seong Joon Ahn Seong Joon Ahn Vincent Tai Katrina P. Winter Neeru Sarin Cynthia A. Toth |
| author_facet | Seong Joon Ahn Seong Joon Ahn Vincent Tai Katrina P. Winter Neeru Sarin Cynthia A. Toth |
| author_sort | Seong Joon Ahn |
| collection | DOAJ |
| description | Pigment epithelial detachment (PED) is well-documented in adult retinal diseases but is rarely reported in neonates. This case describes a preterm infant, born at 31 weeks, who developed PED with thickened choroid at term-equivalent age, detected using handheld OCT. The PED emerged at 39 weeks postmenstrual age, coinciding with inhaled steroid treatment for respiratory distress, and resolved by 41 weeks after steroid discontinuation without structural damage. The temporal relationship suggests an association between steroid use and PED with choroidal changes. This case highlights the value of OCT in detecting retinal and choroidal abnormalities in preterm infants and underscores the potential impact of systemic conditions and medications on the choroid. |
| format | Article |
| id | doaj-art-e41725459b3e4bd4859fde8790bcfc74 |
| institution | DOAJ |
| issn | 2296-858X |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Medicine |
| spelling | doaj-art-e41725459b3e4bd4859fde8790bcfc742025-08-20T03:03:46ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2025-08-011210.3389/fmed.2025.15811911581191Pigment epithelium detachment with thickened choroid in a preterm infant at term-equivalent age: a case reportSeong Joon Ahn0Seong Joon Ahn1Vincent Tai2Katrina P. Winter3Neeru Sarin4Cynthia A. Toth5Department of Ophthalmology, Duke University School of Medicine, Durham, NC, United StatesDepartment of Ophthalmology, Hanyang University Hospital, Hanyang University College of Medicine, Seoul, Republic of KoreaDepartment of Ophthalmology, Duke University School of Medicine, Durham, NC, United StatesDepartment of Ophthalmology, Duke University School of Medicine, Durham, NC, United StatesDepartment of Ophthalmology, Duke University School of Medicine, Durham, NC, United StatesDepartment of Ophthalmology, Duke University School of Medicine, Durham, NC, United StatesPigment epithelial detachment (PED) is well-documented in adult retinal diseases but is rarely reported in neonates. This case describes a preterm infant, born at 31 weeks, who developed PED with thickened choroid at term-equivalent age, detected using handheld OCT. The PED emerged at 39 weeks postmenstrual age, coinciding with inhaled steroid treatment for respiratory distress, and resolved by 41 weeks after steroid discontinuation without structural damage. The temporal relationship suggests an association between steroid use and PED with choroidal changes. This case highlights the value of OCT in detecting retinal and choroidal abnormalities in preterm infants and underscores the potential impact of systemic conditions and medications on the choroid.https://www.frontiersin.org/articles/10.3389/fmed.2025.1581191/fulloptical coherence tomographychoroidpigment epithelium detachmentpretermsteroid |
| spellingShingle | Seong Joon Ahn Seong Joon Ahn Vincent Tai Katrina P. Winter Neeru Sarin Cynthia A. Toth Pigment epithelium detachment with thickened choroid in a preterm infant at term-equivalent age: a case report Frontiers in Medicine optical coherence tomography choroid pigment epithelium detachment preterm steroid |
| title | Pigment epithelium detachment with thickened choroid in a preterm infant at term-equivalent age: a case report |
| title_full | Pigment epithelium detachment with thickened choroid in a preterm infant at term-equivalent age: a case report |
| title_fullStr | Pigment epithelium detachment with thickened choroid in a preterm infant at term-equivalent age: a case report |
| title_full_unstemmed | Pigment epithelium detachment with thickened choroid in a preterm infant at term-equivalent age: a case report |
| title_short | Pigment epithelium detachment with thickened choroid in a preterm infant at term-equivalent age: a case report |
| title_sort | pigment epithelium detachment with thickened choroid in a preterm infant at term equivalent age a case report |
| topic | optical coherence tomography choroid pigment epithelium detachment preterm steroid |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2025.1581191/full |
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