Engineered red blood cell extracellular vesicles for delivery of Dox and siIDO1 enhance targeted chemo-immunotherapy of acute myeloid leukemia

Engineered red blood cell extracellular vesicles for delivery of Dox and siIDO1 enhance targeted chemo-immunotherapy of acute myeloid leukemia

Background As a malignancy of hematopoietic origin, the standard-of-care cytoreductive chemotherapy can not provide satisfactory treatment effect for patients with acute myeloid leukemia (AML). Immunotherapy has received increasing attention in leukemia treatment. However, the immunosuppressive micr...

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Main Authors: Jing Yang, Ling Zhang, Nan Wu, Jiayuan Hu, Jun Ren, Xinyi Chen, Xingyu Wei, Minghui Sun, Ziwei Li, Yongcan Liu, Yan Shu, Genyou Li, Fangfang Jin, Can Lin, Lisha Tang, Zesong Yang
Format: Article
Language:English
Published: BMJ Publishing Group 2025-07-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/13/7/e011148.full
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